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. 2020 Feb 29;22(4):772–788. doi: 10.1093/biostatistics/kxz065

Fig. 3.

Fig. 3.

Manhattan plot of genome-wide association analysis with PBCS using four different methods. PBCS have 2078 invasive breast cancer and 2219 controls. In total, 7 017 694 SNPs on 22 auto chromosomes with MAF more than 5Inline graphic were included in the analysis. ER, PR, HER2, and grade were used to define breast cancer subtypes.