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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2021 Sep 22:ciab850. doi: 10.1093/cid/ciab850

Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine

Elizabeth Fraley 1, Cas LeMaster 1, Santosh Khanal 1, Dithi Banerjee 1, Tomi Pastinen 1, Elin Grundberg 1, Rangaraj Selvarangan 1,#, Todd Bradley 1,#,
PMCID: PMC8522412  PMID: 34551091

Abstract

Determining the duration of immunity to SARS-CoV-2 vaccines is critical for informing the timing of booster immunization. Many host factors could influence both the magnitude and persistence of the antibody response. Here, we showed that SARS-CoV-2 infection before vaccination and age affected the decay of antibody responses to the SARS-CoV-2 mRNA vaccine.

Keywords: SARS-CoV-2, COVID-19, Antibody response, Vaccine

Supplementary Material

ciab850_suppl_Supplementary_Materials

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Supplementary Materials

ciab850_suppl_Supplementary_Materials

Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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