Figure 9.

Concomitant Atg1 and Hsc70-5 knockdown rescued longevity under oxidative stress but was detrimental upon aging in baseline conditions. (A) Lifespan of flies at 25°C following induction of generalized oxidative stress. Flies were fed with 5% hydrogen peroxide sucrose solution. (B) Lifespan of flies at 25°C on the standard diet. (C) The climbing ability of 4 – and 10-d-old flies expressing Atg1 knockdown in the elav>Hsc70-5^KK100233,tub-GAL80^ts background. The standard error of mean and standard deviation are shown as a box and a black line. * p < 0.05, *** p < 0.001