Supplementary Table 3.

Histopathological Assessment of Biofilm-Positive, Biofilm-Negative, and Distal Colonic Biopsies

Cohort/histopathological feature	Total (n = 109)	BF– biopsies (n = 43)	BF+ biopsies (n = 35)	Distal-Bx (n = 31)
IBS
Total n	50	18	19	13
Surface epithelium destruction, n (%)	0 (0)	0 (0)	0 (0)	0 (0)
Inflammatory infiltrate, n (%)	0 (0)	0 (0)	0 (0)	0 (0)
Architecture distortion, n (%)	0 (0)	0 (0)	0 (0)	0 (0)
UC
Total n	30	7	12	11
Surface epithelium destruction, n (%)	1 (3)	0 (0)	1 (8)	0 (0)
Inflammatory infiltrate, n (%)	6 (20)	0 (0)	3 (25)	3 (27)
Architecture distortion, n (%)	7 (23)	0 (0)	5 (42)	2 (18)
Control
Total n	29	18	4	7
Surface epithelium destruction, n (%)	0 (0)	0 (0)	0 (0)	0 (0)
Inflammatory infiltrate, n (%)	0 (0)	0 (0)	0 (0)	0 (0)
Architecture distortion, n (%)	0 (0)	0 (0)	0 (0)	0 (0)