Figure 5.

Breakdown of gene dysregulation among patients, overlaps and differences. a) Venn-diagram shows that some genes are shared among patients. b) Significant changes in gene expression (upregulated and downregulated) in all patients. c) Upregulated genes were used to compute expression profiles (GSEA) showed as GO_terms. d) Significant downregulated genes of interest in patient 1 and 2. e) Significant downregulated genes of interest in patient 1 and 3. f) Histologic subtype of head and neck squamous cell carcinoma tumours presented in this study. (b, d & e) Bars represent average ± S.D. p ≤ 0·05, **p ≤ 0·01, ***p ≤ 0·001, ****p ≤ 0·0001 via one-way ANOVA + Dunnett post-hoc test.