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. 2021 Oct 5;24(11):103222. doi: 10.1016/j.isci.2021.103222

Figure 5.

Figure 5

Regulatory relationship between enriched transcription factors and associated target genes in disease-associated modules

(A) enriched transcription factors in GTEx_M3, cohort1_215_M4, cohort2_75_M3, and cohort3_58_M7.

(B–F) mRNA hepatic expression of the enriched transcription factors including SREBF2, HNF4A, SREBF1, YY1, and KLF13.

(G–I) the regulatory network between enriched transcription factors and associated target genes in cohort1_215_M4, cohort2_75_M3, and cohort3_58_M7, repectively. The regulation between transcription factor and its target was retrieved from the TRRUST database.