Erratum to: “Nuclear Excluded Autism-Associated Phosphatase and Tensin Homolog Mutations Dysregulate Neuronal Growth,” by Fricano-Kugler et al. (Biol Psychiatry 2018; 84:265–277); https://doi.org/10.1016/j.biopsych.2017.11.025.
The authors have discovered that there was a spontaneous mutation that occurred post-cloning in one of the constructs in the paper. Specifically, there was a nonsense truncation in PTEN D326N that resulted in early termination of the protein. This is the reason that PTEN D326N appeared indistinguishable from Pten knockout in all experiments. This affects the interpretation of the results for PTEN D326N but does not affect the overall interpretation of the paper.
