TABLE 1.
MICs of fosfomycin for the resistant mutants and their corresponding complemented strains
| Strain | Fosfomycin MIC (μg/ml) for strain with the following plasmid used for complementationa
: |
|||||
|---|---|---|---|---|---|---|
| None | pSEVA234 | pSEVA234eno | pSEVA234gpmA | pSEVA234gapA | pSEVA234pgk | |
| D457 | 192 | 192 | 128 | 128 | 128 | 192 |
| FOS1 | >1,024 | >1,024 | 192 | ND | ND | ND |
| FOS4 | >1,024 | >1,024 | ND | 192 | ND | ND |
| FOS7 | >1,024 | >1,024 | ND | ND | 128 | ND |
| FOS8 | >1,024 | >1,024 | ND | ND | ND | 192 |
a
ND, not done (each strain was complemented with the wild-type allele of the corresponding mutated gene).