Oral gavage with astaxanthin (ASTX) does not ameliorate blood glucose level, but decreases excessive consumptions of water and feed and lethality in STZ-induced diabetic mice. (A) A scheme illustrating the experimental designs. (B) Blood glucose level and (C) body weight in mice groups were measured at the indicated days after hyperglycemia induction (n = 10). Amounts of (D) water and (E) feed consumption in mice groups were evaluated 30 days after hyperglycemia induction (n = 7). (F) Survival rate (%) of mice groups 12 h after the oral gavage for 60 days with ASTX (n = 10). * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. control group; #
p < 0.05 vs. streptozotocin (STZ) group. BG, blood glucose; BW, body weight; WC, water consumption; FC, feed consumption.