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. 2021 Sep 28;11(10):659. doi: 10.3390/metabo11100659

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Heat map showing differential levels of serum metabolites in COVID-19-positive and COVID-19-recovered patients. The fold changes of the normalized abundances of various metabolites found in the serum samples from COVID-19-positive (CoV) and COVID-19-recovered (Rec) patients were calculated and the metabolite levels that were significantly altered were represented as a heatmap. The fold changes are color coded in the heat map, with red representing a positive fold change (increase) and blue representing a negative fold change (decrease). For several samples, the fold change values were below the ranges specified in the heat map. These values are represented with a cross (X-mark).