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. 2021 Oct 13;13(10):3577. doi: 10.3390/nu13103577

Figure 4.

Figure 4

Salt upregulated CXCL10 and CXCL11 expression in mesangial cell line where melatonin treatment downregulated its expression. RMC (rats’ mesangial cell line) were treated with salt 80 mM with and without 0.5 mM melatonin. CXCL10 (A) and CXCL11 (B) were upregulated by salt treatment and the addition of melatonin reduce this upregulation. The graphs present 6 independent trials. *-p ≤ 0.001 versus control #-p ≤ 0.005 versus salt 80 mM and melatonin 0.5 mM. $-p ≤ 0.05 versus salt 80 mM and melatonin 0.5 mM.