S protein ELISA titration of Group 1 reimmunization, Group 2 (first immunization) and industrial F(ab’)2 concentrate
(A) Titration of pooled sera from all 5 horses of Group 1 upon reimmunization (injections on days 91, 98 and 105).
(B) Titration of pooled sera from all 5 horses of Group 2 (first immunization: 6 weekly injections on days 0–35).
(C) Titration of the pool of plasma collected from Groups 1 and 2 on day 49 and the industrial F(ab’)2 concentrate manufactured under GMP conditions from this pool of plasma. Data are shown as the mean ± standard error of analytical duplicates. The negative control was a pool of preimmune sera of Group 1 animals.