Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 25;13(10):1927. doi: 10.3390/v13101927

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The 3D structures (surface, ribbon, and superimposed views) of the M protein and ORF3a protein interactions with GCP3 at its TUBG1 binding site. For interacting residues, see the corresponding supplement 2D Figure (s) and Table 3. (A) Superimposed (front view) structure showing the SARS-CoV-2 M protein (spring green) binding to GCP3 (sienna) at its TUBG1 (purple) binding position, blocking GCP3-TUBG1 interaction (corresponding to complex 1, Figure S40); (B) its lateral view; and (C) its top views. (D) Front view structure showing the SARS-CoV-2 ORF3a protein (gold) binding to GCP3 (sienna) at its TUBG1 (purple) binding position, blocking GCP3-TUBG1 interaction (corresponding to complex 1, Figure S44); (E) its lateral view; and (F) its top views. (G) Superimposed (front view) complex of both the M and ORF3a protein binding to GCP3 at its TUBG1 binding site; and (H) its front and top views.