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. 2021 Oct 19;13(10):3662. doi: 10.3390/nu13103662

Table 6.

The detailed characteristics of the applied vitamin D supplementation intervention and mental health outcomes for the studies of the irritable bowel syndrome (IBS) patients included to the systematic review.

Ref. Vitamin D Measure Intervention—Vitamin D Supplementation Mental Health Outcome Psychological Measure
[36] 25(OH)D vitamin D level in blood
FFQ
75 µg/day vs. placebo for 12 weeks Quality of life Simple question (“How much has IBS affected your life?”)
[37] 25(OH)D vitamin D level in blood 1250 µg/2 weeks vs. placebo for 6 months Disease-specific quality of life IBS-QoL
[38] Three 24-h dietary recalls 1250 µg/2 weeks vs. placebo for 6 weeks Disease-specific quality of life IBS-QoL
[39] 25(OH)D vitamin D level in blood
3-days dietary recall
1250 µg/week vs. placebo for 6 weeks Disease-specific quality of life IBS-QoL
[40] 25(OH) vitamin D level in blood
3-day dietary records
1250 µg/week vs. placebo for 9 weeks (1) Disease-specific quality of life
(2) Anxiety and depression
(1) IBS-QoL
(2) HADS
[41] 25(OH) vitamin D level in blood 75 µg/day vs. placebo for 12 weeks Disease-specific quality of life IBS-QoL

25-hydroxyvitamin D (25(OH)D); FFQ—Food Frequency Questionnaire; IBS-QoL—Irritable Bowel Disease-Quality of Life questionnaire; HADS—Hospital Anxiety and Depression Scale.