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K-carrageenan promoted matrix mineralization in MC3T3-E1 pre-osteoblasts at day 21 and 28. (A,B) Alizarin red-stained mineralized matrix. (C,D). Quantification of alizarin red-stained mineralized matrix. Values are mean ± SD from four independent experiments. Significant effect of κ-carrageenan, * p < 0.05, *** p < 0.001, **** p < 0.0001. Bar: 1 cm.
