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. 1973 Dec 1;14(5):723–744. doi: 10.1186/BF03547401

Toxicity of Halogenated Oxyquinolines in Dogs. A Clinical Study

I. A Survey of Cases

Toxiciteten av oxikinoliner hos hund. En klinisk studie

Birgitta Lannek 1,✉
PMCID: PMC8559802  PMID: 4772605

Abstract

A survey of 100 cases of oxyquinoline poisoning in dogs is presented. The disease, characterized by hyperexcitability of the CNS with convulsions as well as heart and liver injury, runs an acute course. The mortality (euthanized dogs included) was 30 %. Case-history data showed that the oxyquinoline treatment which preceded the disease was given because the dog had incidental diarrhoea. In most cases the drugs were administered for only 1 day before the dog fell ill. The median time from the last dose to onset of symptoms was 12 hrs. Old dogs were affected more often than expected and also showed higher mortality than did young dogs.

Keywords: convulsions, diarrhoea, dog, halogens, oxyquinolines, poisoning, toxicity

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Footnotes

Supported by grants from the Swedish Medical Research Council.

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