Abstract
This paper deals with an unusually high incidence, i.e. 0.97 % of carcinoma of the small intestine found in Icelandic sheep. The tumours were situated in the jejunum and upper ileum. The macroscopic and microscopic pathology is described and compared with carcinoma of the small intestine of domestic animals and humans.
Aetiological factors are discussed and the possibility of exposure to carcinogenic substances, especially nitrosamines in food concentrates, is suggested.
Finally these findings are discussed in relation to current ideas on carcinogenesis in the intestines.
Keywords: carcinoma, small intestine, sheep, pathology, epizootiology
Sammendrag
En usædvanlig høj incidens, d.v.s. 0.97 %, af carcinom i tyndtarmen observeret hos islandske får rapporteres. Svulsterne var lokaliserede til jejunum og den øverste del af ileum. Den makroskopiske og mikroskopiske patologi beskrives og sammenlignes med carcinom i tyndtarmen hos andre husdyr og mennesker.
Etiologiske faktorer diskuteres og den mulighed drøftes, at fårene er blevet udsat for carcinogene substanser, især nitrosaminer i kraftfoder.
Disse fund diskuteres med henblik på nugældende ideer om carcinogenese i tarmen.
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