Abstract
Reports on discrepancies between local and systemic immunity started to appear about 50 years ago (cf. Tomasi & Bienenstock 1968). Protection against infections has been shown in many cases to be closely related to the antibody content of external secretions and more or less independent from the serum antibody level.
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Acknowledgments
The authors are grateful to Hans Philipsen, D.V.M., Department of Obstetrics and Gynaecology, Royal Veterinary and Agricultural University, Copenhagen, for supplying the experimental material.
References
- Aalund O, Hoerlein A B, Adler H C. The migration test on circulating bovine leukocytes and its possible application in the diagnosis of Johne's disease. Acta vet. scand. 1970;11:331–334. doi: 10.1186/BF03547996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Adler H C. Genital Vibriosis in the Bovine. 1957. [Google Scholar]
- Nairn R C. Fluorescent Protein Tracing. 3rd Ed. Edinburgh and London: S. Livingstone; 1969. [Google Scholar]
- Nansen P, Flagstad T, Pedersen K B. Acta path, microbiol. scand. 1971. Preparation of antisera to bovine immunoglobulin classes by immunization with agar-gel precipitates. [DOI] [PubMed] [Google Scholar]
- Szabo L. Improved sampling method for demonstration of local antibodies in the vagina. Nature (Lond.) 1951;168:171–172. doi: 10.1038/168171c0. [DOI] [PubMed] [Google Scholar]
- Tomasi T B, Bienenstock J. Secretory immunoglobulins. Advana Immunol. 1968;9:1–96. doi: 10.1016/s0065-2776(08)60441-1. [DOI] [PubMed] [Google Scholar]
- Wilkie, B.: The immune response to genital infections. Symp. Bovine Immune System, The Interstate Inn, College Park, Maryland, USA 1970.
