Table 1.
Overview of injected AAV vectors, corresponding titer, and number of animals per group used in this study
| Group | AAV vector | Titer (vg/ml) | Total viral load (vg) | Number of animals |
|---|---|---|---|---|
| D13 | AAV 2/7- CamKIIα(0.4)-intron-hM4D(Gi) | 8.1E + 12 | 4.9E + 10 | 8 |
| M13 | AAV 2/7- CamKIIα(0.4)-intron-mCherry | 2.1E + 13 | 1.2E + 11 | 3 |
| DM13 | AAV 2/7- CamKIIα(0.4)-intron-hM4D(Gi)-mCherry | 2.8E + 13 | 1.7E + 11 | 10 |
| DM12 | AAV 2/7- CamKIIα(0.4)-intron-hM4D(Gi)-mCherry | 9.3E + 11 | 5.6E + 09 | 9 |
| DM11 | AAV 2/7- CamKIIα(0.4)-intron-hM4D(Gi)-mCherry | 2.8E + 11 | 1.7E + 09 | 6 |
D = DREADD, M = mCherry, DM = DREADD-mCherry, vg = vector genomes.