GALNT6 Promotes Tumorigenicity and Metastasis of Breast Cancer Cell via β-catenin/MUC1-C Signaling Pathway: Erratum

In our paper ¹, the image of invaded MDA-MB-231 cells with empty vector transfection (shRNA-NC) in Figure 3C was mis-pasted. The image of invaded MDA-MB-231 cells (Mock) was accidentally used for “shRNA-NC” in Figure 3C. Neither the interpretation nor the conclusion of this work is affected by this error. Figure 3C should be corrected as follows.

Figure 3.

Down-regulation of GALNT6 inhibited the migration and invasion capacity of MDA-MB-231 cells. (A) Wound healing assay and quantification analysis showed that knockdown of GALNT6 significantly inhibited cell migration in MDA-MB-231cells. (B) Transwell migration assay and quantification analysis showed that knockdown of GALNT6 significantly inhibited cell migration in MDA-MB-231 cells. (C) Matrigel invasion assay and quantification analysis showed that knockdown of GALNT6 greatly inhibited invasive abilities of MDA-MB-231 cells. (D-E) Nude mice (n = 5 per group) were injected with 1 × 10⁷ MDA-MB-231 cells (Mock, shRNA-NC or shRNA-T6) via the venous plexus of the eye. After 4 weeks, the mice were sacrificed under anesthesia. (D) The lungs were subjected to Bouin's fixation and photographed. A representative of the experiments is shown. Visible lung metastases nudes were counted. (E) The sections of lungs were stained with H&E. Data are expressed as means ± SEM. *P < 0.05 and **P < 0.01.