Skip to main content
. 2021 Oct 27;599(7884):256–261. doi: 10.1038/s41586-021-04052-7

Extended Data Fig. 4. Reduced genetic diversity of the Tarim_EMBA individuals.

Extended Data Fig. 4

A, a comparison of individual outgroup f3-statistics for the ancient Xinjiang populations and their neighboring populations from Inner Asia, including Tarim_EMBA1 (n = 12), Tarim_EMBA2 (n = 1), ANE (n = 3), Dzungaria_EBA1 (n = 3), Dzungaria_EBA2 (n = 2), West_Siberia_N (n = 3) and Botai_CA (n = 3), which Tarim Basin individuals show the highest affinity to each other. In each boxplot, the box marks the 25th and 75th quartiles of the distribution, respectively, and the horizontal line within the box marks the median. The whisker delineates the maximum and the minimum. B, the cumulative distribution of ROH tracts shows that Tarim_EMBA individuals did not descend from close related parents. C, pairwise mismatch rate (pmr) between individuals in the ancient populations of Xinjiang and its neighboring regions, including all pairs of individuals within the Afanasievo (n = 27), ANE (n = 3), Baikal_EBA (n = 9), Baikal_EN (n = 15), Botai_CA (n = 3), Dzungaria_EBA (n = 5), Dzungaria_EIA (n = 10), Sintashta_MLBA (n = 51), Tarim_EMBA (n = 13), West_Siberia_N (n = 3), as well as present-day isolated populations such as Papuan and Karitiana. Tarim_EMBA individuals uniformly show a much reduced pmr value that is equivalent to the first-degree relatives in Afanasievo or Sintashta_MLBA. The red dotted lines mark the expected pmr value for the given coefficient of relationship (r), ranging from 0 (unrelated) and 1/4 (second degree relatives) to 1/2 (first degree relatives), based on the mean value of pmr among these populations, respectively. In each box plot, the box represents the interquartile range (the 25th and 75th quartiles), and the horizon line within the box represents the median. Black-filled and open circles represent outliers (1.5 times beyond the IQR) and extreme outliers (3 times beyond the IQR), respectively. The whisker delineates the smallest and the largest non-outlier observations. D, Y chromosome phylogeny of the Bronze Age Xinjiang male individuals. Xiaohe male individuals fall into a branch distinct from western Bronze Age steppe pastoralists, such as Afanasievo and Yamnaya. One individual from Beifang falls in a position that is more basal than Xiaohe, but its phylogenetic position cannot be fixed due to low coverage, and its proximate position(s) are instead indicated with an asterisk.