Adviento B, Conner M, Sarkisian A, Walano N, Andersson H, Karlitz JJ. Feasibility of Utilizing PREMM Score for Lynch Syndrome Identification in an Urban, Minority Patient Population. Journal of Primary Care & Community Health. January 2021. doi:10.1177/21501327211020973
In the above-referenced article, the below points were inadvertently missed from the article by the authors. We have now listed the points that needs to be rectified in the published paper:
a) Paragraph 3 sentence has been amended into: “The American College of Gastroenterology (ACG) recommends identification of LS by universal screening of newly diagnosed CRCs for mismatch repair deficiency, or through genetic evaluation of individuals with a family history of LS or who have >2.5% risk of LS based on prediction models.11
b) The following paragraph has been removed from the Introduction section: “It is important to identify individuals who are high risk for LS because it makes genetic confirmation possible, allowing for further testing of at-risk family members and initiation of recommended cancer surveillance. Current indications for genetic evaluation include immunohistochemistry of newly diagnosed colorectal cancer tumors showing microsatellite instability or immunohistochemistry with deficits in MLH, MSH2, MSH6, or PMS2; individuals meeting the Revised Bethesda Guidelines (CRC under the age of 50, tumors with high microsatellite instability, or a family history of LS-associated tumors in 1 first-degree relative or 2 second-degree relatives); endometrial cancer diagnosed under the age of 50; or >5% risk based on prediction screening models, such as PREMM5.12“
C) The below sentences have been removed from the Discussion section: “Current guidelines recommend initiating screening colonoscopy for LS positive individuals at 25 years old and repeat colonoscopy every 1 to 2 years. This requires identifying high-risk individuals who should undergo diagnostic genetic testing.”
Paragraph 1:
“Current guidelines recommend initiating screening colonoscopy for LS positive individuals at 25 years old and repeat colonoscopy every 1 to 2 years. This requires identifying high-risk individuals who should undergo diagnostic genetic testing.”
The authors also note the following potential conflict of interests for Jordan J. Karlitz:
Advisor for Exact Sciences
Former consultant for Myriad Genetics
Equity position in Gastro Girl and GI OnDemand.
Jordan Karlitz should read as Jordan J. Karlitz
The correct affiliations for Jordan J. Karlitz and Nicolette Walano are given below:
Jordan J. Karlitz is affiliated from Department of Gastroenterology, Tulane University School of Medicine, New Orleans, LA, USA
Nicolette Walano is affiliated from Hayward Genetics Center, Tulane University School of Medicine, New Orleans, LA, USA