The causal effect estimates from various Mendelian randomisation methods. The odds ratios of hypothyroidism on IPF are displayed as blue solid box. The 95% confidence intervals are shown as horizontal blue lines. MR, Mendelian randomisation; MR-IVW, MR inverse-variance weighted; MR-RAPS, Robust Adjusted Profile Score; MR-PRESSO, Mendelian Randomisation Pleiotropy RESidual Sum and Outlier; OR, odds ratio; 95%CI, The 95% confidence intervals.