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. 2021 Nov 5;26(21):6688. doi: 10.3390/molecules26216688

Figure 2.

Figure 2

(A) Cytotoxicity of 50 μg/mL FOJ (organic extract from the inflorescences of Cannabis sativa var. Felina 32 collected in June), and of nonintoxicating phytocannabinoids (4 μg/mL cannabidiol, 0.2 μg/mL cannabichromene) and caryophyllane sesquiterpenes (0.05 μg/mL α-humulene, 0.05 μg/mL β-caryophyllene, and 0.03 μg/mL β-caryophyllene oxide), at the corresponding concentrations determined in the extract by GC-MS analysis, in MDA-MB-468 after 24 h exposure. (B) Cytotoxicity of 4 μg/mL cannabidiol alone and in combination with cannabichromene (0.2 μg/mL), α-humulene (0.05 μg/mL), β-caryophyllene (0.05 μg/mL), and β-caryophyllene oxide (0.03 μg/mL) in MDA-MB-468 after 24 h exposure. Data are expressed as mean ± SEM of at least three independent experiments with three technical replicates (n = 9); * p < 0.05 and *** p < 0.001, significant difference respect to the control; °°° p < 0.001, significant difference respect to cannabidiol (ANOVA + Dunnett’s Multiple Comparison PostTest).