Table 1.
Assessment of anti-inflammatory activity of Terminalia arjuna extract and Ibuprofen through paw edema test in a rat model (∗ presents the level of significance of result). Here, the percentage of inhibition of inflammatory mediation was measured by collecting rat's paw before and after injection shown in Eq. (2).
| Group | Time |
||||
|---|---|---|---|---|---|
| 0 Minute (Just before carrageenan injection) | 1 hour (just before treatment) | 2 Hours | 3 hours | 4 hours | |
| N.C | 116.28 ± 2.68 | 116.24 ± 2.49 | 116.28 ± 2.68 | 116.28 ± 2.68 | 116.28 ± 2.68 |
| Car | 117.28 ± 5.05 | 145.06 ± 3.67 | 159.82 ± 4.98 | 171.38 ± 2.21 | 184.54 ± 4.83 |
| Car + Ib10 | 114.9 ± 1.86 | 143.5 ± 4.14 | 132.44 ± 13.3∗∗ (17.1%) | 122.08 ± 2.21∗∗ (28.77%) | 118.32 ± 6.10∗∗ (35.88%) |
| Car + Ib20 | 119.54 ± 3.51 | 151.62 ± 4.77 | 127.48 ± 4.58∗∗ (20.23%) | 120.12 ± 5.82∗∗ (29.9%) | 117.02 ± 5.96∗∗ (36.59%) |
| Car + Ib25 | 114.2 ± 4.17 | 150.76 ± 3.55 | 122.16 ± 7.14∗∗ (23.56%) | 117.02 ± 4.73∗∗ (31.72%) | 114.42 ± 4.17∗∗ 37.99% |
| Car + TA500 | 117.86 ± 5.15 | 142.8 ± 4.92 | 136.5 ± 2.56∗∗ (14.59%) | 126.34 ± 3.58∗∗ (26.28%) | 122.98 ± 3.62∗∗ (33.36%) |
| Car + TA750 | 109.98 ± 3.42 | 148 ± 2.98 | 131.26 ± 2.19∗∗ (17.87%) | 124.36 ± 2.19∗∗ 27.44% |
116.16 ± 3.85∗∗ 37.05% |
| Car + TA1000 | 111 ± 2.09 | 146.92 ± 4.16 | 122.96 ± 2.89∗∗ (23.06%) | 117.56 ± 2.25∗∗ (31.40%) | 112.68 ± 2.97∗∗ (39.26%) |
| Ib10 | 114.9.±1.26 | 116.2 ± 2.33 | 114.55 ± 1.45 | 114.7.28 ± 2.05 | 114.77 ± 1.58 |
| Ib20 | 118.6.±3.1 | 117.8 ± 2.8 | 117.8. ±2.62 | 117.8 ± 2.64 | 116.9 ± 2.03 |
| Ib25 | 115.53 ± 2.3 | 114.9 ± 2.5 | 115.7 ± 2.35 | 115.5 ± 2.29 | 115.49 ± 2.52 |
| TA500 | 118.7 ± 2.66 | 117.9 ± 2.0 | 118.4 ± 3.2 | 118.55 ± 2.25 | 118.6 ± 2.61 |
| TA750 | 113.59 ± 2.4 | 113.59 ± 2.6 | 113.48 ± 1.94 | 114.33 ± 2.24 | 114.24 ± 2.23 |
| TA1000 | 113.34 ± 2.2 | 113,29 ± 1.35 | 113.44 ± 2.1 | 112.99 ± 1.79 | 113.54 ± 2.10 |