Abstract
Introduction:
In the U.S., state-level household firearm ownership is strongly associated with firearm suicide mortality rates. Whether recent increases in firearm suicide are explained by state-level household firearm ownership rates, and trends, remains unknown.
Methods:
Mortality data from the U.S. National Vital Statistics System and an estimate of state-level household firearm ownership rate were used to conduct hierarchical age–period–cohort (random-effects) modeling of firearm suicide mortality between 2001 and 2016. Models were adjusted for individual-level race and sex, and state-level poverty rate, unemployment rate, median household income in U.S. dollars, population density, and elevation.
Results:
Between 2001 and 2016, crude national firearm suicide mortality rate increased from 6.8 to 8.0/100,000 and household firearm ownership rate remained relatively stable, at around 40%. Both variables were markedly heterogeneous and correlated at the state level. Age–period– cohort models revealed period effects (affecting people across ages) and cohort effects (affecting specific birth cohorts) underlying recent increases in firearm suicide. Individuals born after 2000 had higher firearm suicide rates than most cohorts born before. A 2001–2006 decreasing period effect was followed, after 2009, by an increasing period effect that peaked in 2015. State-level household firearm ownership rates, and trends, did not explain cohort effects and only minimally explained period effects.
Conclusions:
State-level firearm ownership rates largely explain state-level differences in firearm suicide, but only marginally explain recent increases in firearm suicide. Although firearms in the home increase firearm suicide risk, the recent national rise in firearm suicide might be the result of broader, more distal causes of suicide risk.
INTRODUCTION
Suicide mortality risk is highly determined by choice of suicide method. For instance, suicide attempts involving use of a firearm are nearly always lethal and 40 times more lethal than intentional overdoses.1 Moreover, 90% of attempt survivors do not go on to die by suicide later in life.2,3 For these reasons, lethality of the suicide methods that people routinely have at hand is a key actionable determinant of long-term survival. Accordingly, lethal means restriction is a leading evidence-based strategy for suicide prevention,4 largely responsible for recent decreases in global suicide rates.5
In the U.S., the country with the highest per-capita prevalence of civilian-owned firearms,6 the majority of firearm deaths are intentionally self-inflicted and half of suicide deaths involve firearm use.7 In addition, suicide mortality rates in the U.S. have increased by >30% over the last 2 decades, across all suicide methods, constituting a major public health crisis.8
A large body of well-designed studies indicates that firearm ownership is associated with higher risk of death by firearm suicide at the state,9 household,10 and individual11,12 levels, across sociodemographic groups.12 Accordingly, substantial attention has been directed toward firearm ownership as a salient target for suicide prevention efforts.
Notwithstanding, 2 aspects of the association between firearm ownership and firearm suicide risk in the U.S. remain poorly understood, despite public health and clinical implications (e.g., for guiding preventative policies; developing, implementing, or scaling up preventative interventions; and identifying high-risk sociodemographic groups). First, though evidence from the 1980s and 1990s suggests that declines in firearm ownership rates were directly associated with declines in overall and firearm suicide rates,13 the role of trends in firearm ownership rates in recent increases in firearm suicide rates has not been explored. Second, decomposing suicide mortality trends across age–period–cohort effects can help identify potential underlying actionable mechanisms. Established age–period–cohort models of suicide in the U.S. indicate that increases in firearm suicide mortality are the result of both period and birth cohort effects,14 with period effects driving much of the increases in recent years (indicating that suicide mortality is increasing across all ages). However, the extent to which recent trends in firearm ownership rates may have impacted the period and cohort effects underlying recent increases in firearm suicide mortality rate has not been analyzed.
Here, the role of state-level differences and trends in household firearm ownership on recent suicide mortality rates in the U.S. are examined, using hierarchical age–period–cohort (random-effects) models.
METHODS
Study Sample
Suicide mortality data from the U.S. National Vital Statistics System were used for the main analysis. Though mortality data are available through 2019, data on firearm ownership by state are available through 2016; thus, the time period of outcome data was matched to the time period of exposure data. Suicide mortality data through 2018 were included in a sensitivity analysis. These data comprise basic clinical and demographic information retrieved from all deaths certificated in the U.S. including immediate and underlying cause/s of death, age, sex (male, female), race (Black or African American, Asian or Pacific Islander, American Indian or Alaska Native, and White), and county of residence.15 Deaths were designated as attributable to suicide based on ICD-10 underlying cause of death codes X60−X84, Y87.0, and U03, following guidelines from the National Center for Health Statistics.8 Analyses were further restricted only to firearm suicides among decedents aged 10−84 years, given the lack of firearm suicides prior to age 10 years and unavailability of disaggregated data after age 84 years. State-level population data from the National Center for Health Statistics, including intercensal (1999−2009)16,17 and postcensal (2010−2018)18 estimates, were used to calculate unadjusted mortality rates for populations aged 10−84 years.
Measures
To measure state-level household firearm ownership rate, a modification of the factor score developed by the Research and Development Corporation19 was used. The original household firearm ownership rate score estimates the state-level proportion of adults who live in a household with a firearm annually between 1980 and 2016 and is based on 9 measures: 4 direct measures of household gun ownership from several non-annual representative surveys (the Behavioral Risk Factor Surveillance System, Gallup, the General Social Survey, and Pew Research Center) and 5 indirect measures (male and female proportions of firearm suicides/total suicides, hunting license rate, Guns & Ammo per capita subscribers, and background check rate). In addition, the score includes 3 exogenous factors: indicators of states with laws regulating universal background checks and firearm purchase permits, and 3 time splines (for hunting licenses). A modified estimate of the state-level proportion of adults who live in a household with a firearm (hereafter called household firearm ownership rate) for the 1999−2016 period, excluding the item on firearm suicides/total suicides (which was colinear with the outcome), was calculated using code provided by the Research and Development Corporation and applied in all models. Notably, the original and modified household firearm ownership rate scores were highly correlated (r =0.98, p<0.001).
The following additional state-level covariates20 were used, with yearly data from 2001 to 2018: proportion of adult population unemployed, retrieved from the U.S. Bureau of Labor Statistics21; proportion of families living in poverty, median household income in 2014 U.S. dollars, and population density in people per square mile, all provided by GeoLytics22; and mean elevation in feet, retrieved from the U.S. Census.23 Data from GeoLytics, including proportion of families living in poverty, population density, and median household income, were not available for Alaska.
Statistical Analysis
First, descriptive analyses of spatiotemporal variation in firearm suicide mortality rates and household firearm ownership in U.S. states between 1999 and 2016 were conducted. Then, age– period–cohort effects were modeled. Age–period–cohort analyses disentangle variation in trends over time related to 3 components: age effects (resulting from factors specific to development stages), period effects (resulting from external factors that impact subjects across age and birth cohort), and cohort effects (resulting from the environmental exposures shared by individuals born into a specific historical context over the life course).24 The goal was to understand the impact of state-level household firearm ownership on age–period–cohort effect estimates. Hence, hierarchical cross-classified random effect models, which allow for the inclusion of covariates,25,26 were implemented. All models included individual-level variables for race and sex, and were restricted to the 2001−2016 period and all states excluding Alaska based on covariate information availability. Three models were estimated where age was categorized in 5-year groups and included as a Level-1 variable, and period and cohort were estimated as random intercept effects. For the first model, state was included as a fixed term, given notable differences in firearm suicide rates across states. For the second model, the fixed term for state was excluded and the following state-level covariates were included: poverty rate, unemployment rate, median household income, population density, and mean elevation. For the third model, state-level household firearm ownership rate was added to the set of covariates included in the second model. Of note, household firearm ownership rate was correlated with poverty rate (r =0.28, p<0.001), unemployment rate (r = −0.16, p<0.001), and median household income (r = −0.71, p<0.001) at the state level. State-level household firearm ownership rates remained relatively stable over the study period; variation in household firearm ownership was largely explained by between-state differences (state intraclass correlation coefficient=0.94) rather than betweenperiod differences (period intraclass correlation coefficient=0.13). Hence, household firearm ownership rate was entered in the model categorized in octiles, based on each state’s yearly household firearm ownership rate classified relative to the range of rates for all states (excluding Alaska) over the 2001−2016 period. Period and cohort (random) effects were centered to ease interpretation.
For each model, the period effect’s median odds ratio (MOR) was estimated to quantify the period effect variability that remained unexplained by the other set of variables included in the model. The MOR provides an estimate of the differences between outcomes by Level-2 random effects; an increased MOR for a particular Level-2 effect (i.e., cohort, period) indicates that more of the variation in firearm suicide rates is due to variation in the Level-2 effect. A decrease in the MOR after including a covariate in the model (i.e., state-level firearm ownership by year) indicates that the covariate explained variation in the Level-2 effect. The remaining magnitude of the MOR indicates the amount of variance in the outcome due to the Level-2 effect that is not explained by the covariates. Accordingly, the difference in MOR between the second and third models quantifies the role of state-level firearm household ownership rate on recent trends and period/cohort effects in firearm suicide mortality.
Data cleaning and descriptive analyses were completed in R, version 4.0.3.27 Age−period−cohort models were completed in SAS, version 9.4.28
Two prespecified sensitivity analyses were conducted. First, the third model was repeated, including the household firearm ownership rate as a continuous variable. Second, capitalizing on the temporal stability of household firearm ownership rate, models were extended through 2018 by carrying forward the 2016 household firearm ownership rate, using 2016−2018 data on firearm suicide mortality rates, poverty rate, unemployment rate, and median household income.
RESULTS
Between 1999 and 2016, U.S. firearm suicide mortality rate for individuals aged 10−84 years increased from 6.8 to 8.0 deaths per 100,000 people as a result of an initial gradual downward trend between 1999 and 2006 followed by an increase between 2007 and 2016 (Figure 1, right axis). National estimates of household firearm ownership rate remained relatively stable over the same period (Figure 1, left axis), indicating that around 40% of adults lived in a household with a firearm.
Figure 2 represents state-level firearm suicide mortality rates and household firearm ownership rates for the whole study period, ranked from lowest to highest: Both variables were notably correlated and substantially heterogeneous across states (r =0.81, p<0.001). States with the highest firearm suicide mortality rates (e.g., Montana, Alaska, or Wyoming) had the highest estimates of household firearm ownership; and states with the lowest firearm suicide mortality rates (e.g., New Jersey or Massachusetts) had the lowest estimates of household firearm ownership.
Appendix Table 1 and Appendix Figure 1 represent the trends over time in firearm suicide rates and household firearm ownership by state. Between 1999 and 2016, firearm suicide rates increased in 41 states, and household firearm ownership rates increased in 28 states.
Recent increases in firearm suicide rates were due to both cohort and period effects. Individuals born after 2000 had higher firearm suicide rates than most cohorts born between 1930 and 2000, with random effect coefficients of around 0.15 (Figure 3). Notably, cohort effects remained unchanged across differently specified models: subtraction and addition of state-level covariates, including household firearm ownership rate, did not account for firearm suicide mortality increases among recently born cohorts.
A decreasing period effect between 2001 and 2006 was followed by a stable period between 2006 and 2009 and a subsequent increasing period effect that peaked, in fully adjusted models, in 2015 with a random effect coefficient of around 0.16 (Figure 4). Inclusion of state-level covariates did modify the variability of period effect estimates. The first model, including only a fixed term for state, yielded a period effect (MOR=1.06). The second model, including state-level poverty rate, unemployment rate, median household income, population density, and mean elevation resulted on a higher period effect variability (MOR=1.15). Part of the period effect variability could be explained by state-level household firearm ownership rate, as inclusion of this covariate in the third model resulted on a period effect (MOR=1.11).
Results did not change across the 2 pre-specified sensitivity analyses. Inclusion of state-level household firearm ownership rate as a continuous variable resulted in similar cohort and period effects (Appendix Figures 2 and 3), for a period effect (MOR=1.09) in the fully adjusted model including state-level poverty rate, unemployment rate, median household income, mean elevation, population density, and household firearm ownership rate. Extension of the study period from 2001−2016 to 2001−2018 also yielded similar cohort and period effects (Appendix Figures 4 and 5). Again, inclusion of state-level household firearm ownership rate did not lead to variation in cohort effects but reduced the variability of period effect estimates, from a period effect (MOR=1.16) in the model including state-level poverty rate, unemployment rate, median household income, population density, and mean elevation to a period effect (MOR=1.12) following additional inclusion of household firearm ownership rate.
DISCUSSION
Between 1999 and 2018, firearm suicide mortality rates increased in the U.S. nationally and in 41 of 50 states owing to cohort and period effects: Firearm suicide risk increased disproportionately (1) among recently born cohorts in comparison with all birth cohorts since 1930 and (2) across age groups and birth cohorts, after 2009. The proportion of people who lived in a household with a firearm, however, remained relatively stable at around 40%, increasing in 28 states between 1999 and 2016. These findings indicate that state-level household firearm ownership rates and trends could explain a proportion of period effects but appeared unrelated to cohort effects in firearm suicide mortality, which has important implications for prevention efforts.
State-level household firearm ownership rates were spatially correlated with state-level firearm suicide mortality rates. State-level household firearm ownership rates also partially explained the recent increase in firearm suicide risk over time across age groups and birth cohorts (e.g., the period effect). Both findings are in line with a large body of literature examining the ecological association between firearm ownership and suicide mortality9−11,29,30 and serve to highlight the importance of firearm ownership as a determinant of access to lethal means for people experiencing a suicidal crisis.31 Reducing the availability of highly prevalent lethal means32,33 in general and of firearms34−38 in particular has proven effective at lowering method-specific and overall suicide mortality rates in several high-income countries.24−29
In the U.S., where rapid reductions in the overall level of firearm ownership are unlikely given the entrenched historical, political, social, and legal climate (sometimes referred to as “gun culture”39−41), clinical and legislative efforts to reduce access to firearms during suicidal crises might focus on more proximal determinants of firearm suicide, such as method for firearm storage42,43 or individual interventions for at-risk individuals including lethal means counseling.31 Policy efforts such as red flag laws, which allow court petitions to temporarily prohibit firearm purchase and possession to individuals deemed dangerous to self or others, have broad public support and are associated with modest reductions in firearm suicide rates.44
A substantial proportion of the period effect in firearm suicide mortality, however, could not be explained by rates and trends in household firearm ownership. There was a notable increase in firearm suicide mortality risk among recent birth cohorts, in line with recent research,45 and consistent with recent increases in depression and suicidal behaviors among U.S. adolescents and young adults.48−50 State-level firearm ownership rate and trends did not modify this cohort effect. This is in keeping with evidence indicating that suicide mortality increased recently in the U.S. across sociodemographic groups, birth cohorts, and methods—in fact, recent increases in suicide mortality in the U.S. were starker for non-firearm than firearm suicide,8 leading to the observation that the proportion of suicides involving use of a firearm has decreased slightly because of faster increases in other suicide methods. Taken together, this evidence points to broader, more distal factors, such as consequences of the opioid overdose epidemic,45 downstream consequences of the 2008 recession,46 or a general decline in social connectedness.47
Importantly, this finding should not lead to an underestimation of the importance of access to firearms as an actionable public health target for reducing suicide risk, because firearm ownership rates mediate the relationship between distal social factors and firearm suicide mortality risk. Although recent stable firearm ownership rates do not seem to have had a role in contemporary risk increases among young individuals, a large body of evidence links variations in firearm availability to variations in firearm suicide risk, especially among youth. Recent reports,51 indicating that firearm purchases have increased markedly during the initial phases of the coronavirus disease 2019 (COVID-19) pandemic, should be cause for concern over its potential contribution to longer-term trends in suicide mortality rates.
Limitations
This study has potential limitations. First, suicides may be under-reported owing to certification errors.52 Second, the original estimate of state-level household firearm ownership rate was recalculated, after excluding an item measuring the proportion of suicides involving a firearm to prevent collinearity with the outcome. Notably, the original and the modified estimated rates were very highly correlated. Third, the ecological nature of the associations somewhat hinders interpretation. Future studies should examine the role of firearm ownership on suicide using more granular spatial units or at the individual level. Fourth, as data did not include information on firearm ownership after 2016, sensitivity analyses extending results through 2018 rely on the assumption that household firearm ownership rate remained stable between 2016 and 2018. This assumption, however, is reasonable according to recent surveys.53,54 Fifth, the moderating role of certain specific firearm access variables that may be associated with firearm suicide risk, such as ownership of multiple firearms or of particular types of firearms,55 proportion of first-time firearm buyers,11 or firearm storage practices,43 could not be explored. Although evidence strongly indicated that firearm ownership increases firearm suicide risk regardless of number or type of firearms owned and of storage practices,56,57 future research should examine the role of these variables on recent increases in suicide mortality. Last, the analysis also did not examine state firearm policies that may contribute to the reported associations.
CONCLUSIONS
Recent increases in firearm suicide mortality were due to both cohort and period effects: Individuals born after 2000 had higher suicide rates than most 1930−2000 birth cohorts and firearm suicide risk increased after 2009 across age groups and birth cohorts. State-level firearm ownership rates, which remained relatively stable over the last 2 decades, largely explain state-level differences in firearm suicide but only marginally explain recent increases in firearm suicide: State-level firearm ownership rates, and trends, did not explain cohort effects and only minimally explained period effects. Although firearms in the home increase the risk of firearm suicide, the recent national rise in firearm suicide may also involve increases in other threats to health, including consequences of the opioid overdose epidemic,45 downstream consequences of the 2008 recession,46 or a general decline in social connectedness.47 Minimizing the risks due to firearm ownership remains an important part of suicide prevention, but other efforts targeting broader, more distal causes of suicide risk are also urgently needed.
Supplementary Material
ACKNOWLEDGMENTS
This work was funded by the National Institute of Mental Health (R01-MH121410). The funder/sponsor had no role in study design; collection, analysis, and interpretation of data; writing the report; or the decision to submit the report for publication.
Footnotes
JS and Columbia University declare partial ownership of SK Analytics. SK was a consultant for SK Analytics. JS was a consultant for BNI. KK has been compensated as an expert witness in litigation. No other disclosures were reported.
Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
REFERENCES
- 1.Spicer RS, Miller TR. Suicide acts in 8 states: incidence and case fatality rates by demographics and method. Am J Public Health. 2000;90(12):1885–1891. 10.2105/ajph.90.12.1885. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Simon OR, Swann AC, Powell KE, Potter LB, Kresnow MJ, O’Carroll PW. Characteristics of impulsive suicide attempts and attempters. Suicide Life Threat Behav. 2001;32(1 suppl):49–59. 10.1521/suli.32.1.5.49.24212. [DOI] [PubMed] [Google Scholar]
- 3.Deisenhammer EA, Ing C-M, Strauss R, Kemmler G, Hinterhuber H, Weiss EM. The duration of the suicidal process: how much time is left for intervention between consideration and accomplishment of a suicide attempt? J Clin Psychiatry. 2009;70(1):19–24. 10.4088/jcp.07m03904. [DOI] [PubMed] [Google Scholar]
- 4.Yip PSF, Yousuf S, Chang S-S, Caine E, Wu KC-C, Chen Y-Y. Means restriction for suicide prevention. Lancet. 2012;379(9834):2393–2399. 10.1016/s0140-6736(12)60521-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Naghavi M. Global, regional, and national burden of suicide mortality 1990 to 2016: systematic analysis for the Global Burden of Disease Study 2016. BMJ. 2019;364:l94. 10.1136/bmj.l94. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Hepburn L, Miller M, Azrael D, Hemenway D. The US gun stock: results from the 2004 National Firearms Survey. Inj Prev. 2007;13(1):15–19. 10.1136/ip.2006.013607. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Centers for Disease Control and Prevention. Web-based Injury Statistics Query and Reporting System (WISQARS). www.cdc.gov/injury/wisqars. Accessed June 16, 2021.
- 8.Hedegaard H, Curtin SC, Warner M. Suicide mortality in the United States, 1999−2019. NCHS Data Brief. 2021;398. 10.15620/cdc:101761. [DOI] [PubMed] [Google Scholar]
- 9.Miller M, Lippmann SJ, Azrael D, Hemenway D. Household firearm ownership and rates of suicide across the 50 United States. J Trauma Acute Care Surg. 2007;62(4):1029–1035. 10.1097/01.ta.0000198214.24056.40. [DOI] [PubMed] [Google Scholar]
- 10.Miller M, Azrael D, Hemenway D. Household firearm ownership and suicide rates in the United States. Epidemiology. 2002;13(5):517–524. 10.1097/00001648-200209000-00006. [DOI] [PubMed] [Google Scholar]
- 11.Studdert DM, Zhang Y, Swanson SA, et al. Handgun ownership and suicide in California. N Engl J Med. 2020;382(23):2220–2229. 10.1056/nejmsa1916744. [DOI] [PubMed] [Google Scholar]
- 12.Swanson SA, Eyllon M, Sheu Y-H, Miller M. Firearm access and adolescent suicide risk: toward a clearer understanding of effect size. Inj Prev. 2021;27(3):264–270. 10.1136/injuryprev-2019-043605. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 13.Miller M, Azrael D, Hepburn L, Hemenway D, Lippmann SJ. The association between changes in household firearm ownership and rates of suicide in the United States, 1981− 2002. Inj Prev. 2006;12(3):178–182. 10.1136/ip.2005.010850. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 14.Martínez-Alés G, Pamplin JR, Rutherford C, et al. Age, period, and cohort effects on suicide death in the United States from 1999 to 2018: moderation by sex, race, and firearm involvement. Mol Psychiatry. In press. Published April 7, 2021. 10.1038/s41380-021-01078-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.National Research Council (US) Committee on National Statistics. Vital Statistics: Summary of a Workshop. Washington, DC: National Academies Press (US); 2009. http://www.ncbi.nlm.nih.gov/books/NBK219877/. Accessed January 18, 2021. [PubMed] [Google Scholar]
- 16.National Center for Health Statistics. Intercensal estimates of the resident population of the United States for July 1, 1990−July 1, 1999. http://www.cdc.gov/nchs/nvss/bridged_race.htm. Accessed June 16, 2021.
- 17.National Center for Health Statistics. Intercensal Estimates of the Resident Population of the United States for July 1, 2000-July 1, 2009. http://www.cdc.gov/nchs/nvss/bridged_race.htm. Accessed June 16, 2021.
- 18.National Center for Health Statistics. Vintage 2019 postcensal estimates of the resident population of the United States for April 1, 2010, July 1, 2010-July 1, 2019. http://www.cdc.gov/nchs/nvss/bridged_race.htm. Accessed June 16, 2021. [Google Scholar]
- 19.Schell TL, Peterson S, Vegetabile BG, Scherling A, Smart R, Morral AR. State-Level Estimates of Household Firearm Ownership. Santa Monica, CA: RAND Corporation; 2020. 10.7249/tl354. [DOI] [Google Scholar]
- 20.Martinez-Ales G, Hernandez-Calle D, Khauli N, Keyes KM. Why Are Suicide Rates Increasing in the United States? Towards a Multilevel Reimagination of Suicide Prevention. In: Baca-Garcia E, ed. Behavioral Neurobiology of Suicide and Self Harm. Current Topics in Behavioral Neurosciences. Springer International Publishing; 2020:1–23. 10.1007/7854_2020_158. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 21.U.S. Bureau of Labor Statistics. Local Area Unemployment Statistics. https://www.bls.gov/lau/tables.htm. Accessed June 16, 2021.
- 22.Census Data. GeoLytics. https://geolytics.com/census-data. Accessed January 25, 2021.
- 23.Statistical Abstract of the United States: 2012. U.S. Census Bureau. https://ww.census.gov/library/publications/2011/compendia/statab/131ed.html. Accessed January 25, 2021. [Google Scholar]
- 24.Keyes KM, Utz RL, Robinson W, Li G. What is a cohort effect? Comparison of three statistical methods for modeling cohort effects in obesity prevalence in the United States, 1971‒2006. Soc Sci Med. 2010;70(7):1100–1108. 10.1016/j.socscimed.2009.12.018. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 25.Yang Y, Land KC. A mixed models approach to the age-period-cohort analysis of repeated cross-section surveys, with an application to data on trends in verbal test scores. Sociol Methodol. 2006;36(1):75–97. 10.1111/j.1467-9531.2006.00175.x. [DOI] [Google Scholar]
- 26.Yang Y, Land K. Chapter 7. Mixed effects models: hierarchical APC-cross-classified random effects models (HAPC-CCREM), Part I: the basics. In: Yang Y, Land K, eds. Age-period-cohort analysis: new models, methods, and empirical applications. Chapman and Hall/CRC Interdisciplinary Statistics, 2013. 10.1201/b13902-7. [DOI] [Google Scholar]
- 27.R Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing; 2019. https://www.R-project.org/. [Google Scholar]
- 28.SAS Institute Inc. SAS Version 9.4. Cary, NC: SAS Institute Inc.; 2014. [Google Scholar]
- 29.Knopov A, Sherman RJ, Raifman JR, Larson E, Siegel MB. Household gun ownership and youth suicide rates at the state level, 2005‒2015. Am J Prev Med. 2019;56(3):335–342. 10.1016/j.amepre.2018.10.027. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 30.Kaplan MS, Geling O. Firearm suicides and homicides in the United States: regional variations and patterns of gun ownership. Soc Sci Med. 1998;46(9):1227–1233. 10.1016/s0277-9536(97)10051-x. [DOI] [PubMed] [Google Scholar]
- 31.Barber CW, Miller MJ. Reducing a suicidal person’s access to lethal means of suicide: a research agenda. Am J Prev Med. 2014;47(3 suppl 2):S264–S272. 10.1016/j.amepre.2014.05.028. [DOI] [PubMed] [Google Scholar]
- 32.Hawton K, Bergen H, Simkin S, et al. Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses. BMJ. 2013;346:f403. 10.1136/bmj.f403. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 33.Gunnell D, Knipe D, Chang S-S, et al. Prevention of suicide with regulations aimed at restricting access to highly hazardous pesticides: a systematic review of the international evidence. Lancet Glob Health. 2017;5(10):e1026–e1037. 10.1016/s2214-109x(17)30299-1. [DOI] [PubMed] [Google Scholar]
- 34.Reisch T, Steffen T, Habenstein A, Tschacher W. Change in suicide rates in Switzerland before and after firearm restriction resulting from the 2003 “Army XXI” reform. Am J Psychiatry. 2013;170(9):977–984. 10.1176/appi.ajp.2013.12091256. [DOI] [PubMed] [Google Scholar]
- 35.Gagné M, Robitaille Y, Hamel D, St-Laurent D. Firearms regulation and declining rates of male suicide in Quebec. Inj Prev. 2010;16(4):247–253. 10.1136/ip.2009.022491. [DOI] [PubMed] [Google Scholar]
- 36.Kapusta ND, Etzersdorfer E, Krall C, Sonneck G. Firearm legislation reform in the European Union: impact on firearm availability, firearm suicide and homicide rates in Austria. Br J Psychiatry. 2007;191(3):253–257. 10.1192/bjp.bp.106.032862. [DOI] [PubMed] [Google Scholar]
- 37.Chapman S, Alpers P, Agho K, Jones M. Australia’s 1996 gun law reforms: faster falls in firearm deaths, firearm suicides, and a decade without mass shootings. Inj Prev. 2006;12(6):365–372. 10.1136/ip.2006.013714. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 38.Lubin G, Werbeloff N, Halperin D, Shmushkevitch M, Weiser M, Knobler HY. Decrease in suicide rates after a change of policy reducing access to firearms in adolescents: a naturalistic epidemiological study. Suicide Life Threat Behav. 2010;40(5):421–424. 10.1521/suli.2010.40.5.421. [DOI] [PubMed] [Google Scholar]
- 39.Kalesan B, Villarreal MD, Keyes KM, Galea S. Gun ownership and social gun culture. Inj Prev. 2016;22(3):216–220. 10.1136/injuryprev-2015-041586. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 40.Abdalla SM, Keyes KM, Galea S. A public health approach to tackling the role of culture in shaping the gun violence epidemic in the United States. Public Health Rep. 2021;136(1):6–9. 10.1177/0033354920965263. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 41.Boine C, Siegel M, Ross C, Fleegler EW, Alcorn T. What is gun culture? Cultural variations and trends across the United States. Humanit Soc Sci Commun. 2020;7(1):1–12. 10.1057/s41599-020-0520-6. [DOI] [Google Scholar]
- 42.Simonetti JA, Azrael D, Rowhani-Rahbar A, Miller M. Firearm storage practices among American Veterans. Am J Prev Med. 2018;55(4):445–454. 10.1016/j.amepre.2018.04.014. [DOI] [PubMed] [Google Scholar]
- 43.Shenassa ED, Rogers ML, Spalding KL, Roberts MB. Safer storage of firearms at home and risk of suicide: a study of protective factors in a nationally representative sample. J Epidemiol Community Health. 2004;58(10):841–848. 10.1136/jech.2003.017343. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 44.Kivisto AJ, Phalen PL. Effects of risk-based firearm seizure laws in Connecticut and Indiana on suicide rates, 1981−2015. Psychiatr Serv. 2018;69(8):855–862. 10.1176/appi.ps.201700250. [DOI] [PubMed] [Google Scholar]
- 45.Martinez-Ales G, Pamplin IIJR, Rutherford C, Gimbrone C, Kandula S, Olfson M, Gould MS, Shaman J, Keyes KM. Age, period, and cohort effects on suicide death in the United States from 1999 to 2018: moderation by sex, race, and firearm involvement. Mol Psychiatry. In press. Online April 7, 2021. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 46.Reeves A, Stuckler D, McKee M, Gunnell D, Chang S-S, Basu S. Increase in state suicide rates in the USA during economic recession. Lancet. 2012;380(9856):1813–1814. 10.1016/s0140-6736(12)61910-2. [DOI] [PubMed] [Google Scholar]
- 47.Holt-Lunstad J. The potential public health relevance of social isolation and loneliness: prevalence, epidemiology, and risk factors. Public Policy Aging Rep. 2017;27(4):127–130. 10.1093/ppar/prx030. [DOI] [Google Scholar]
- 48.Mojtabai R, Olfson M, Han B. National trends in the prevalence and treatment of depression in adolescents and young adults. Pediatrics. 2016;138(6).:e20161878 10.1542/peds.2016-1878. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 49.Plemmons G, Hall M, Doupnik S, et al. Hospitalization for suicide ideation or attempt: 20082-2015. Pediatrics. 2018;141(6):e20172426. 10.1542/peds.2017-2426. [DOI] [PubMed] [Google Scholar]
- 50.Keyes KM, Gary D, O’Malley PM, Hamilton A, Schulenberg J. Recent increases in depressive symptoms among US adolescents: trends from 1991 to 2018. Soc Psychiatry Psychiatr Epidemiol. 2019;54(8):9872–996. 10.1007/s00127-019-01697-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 51.McKnight PBL and R. Three million more guns: the Spring 2020 spike in firearm sales. Brookings. https://www.brookings.edu/blog/up-front/2020/07/13/three-million-moreguns-the-spring-2020-spike-in-firearm-sales/. Published July 13, 2020. Accessed February 1, 2021. [Google Scholar]
- 52.De Leo D. Can we rely on suicide mortality data? Crisis. 2015;36(1):1–3. 10.1027/0227-5910/a000315. [DOI] [PubMed] [Google Scholar]
- 53.Guns. Gallup. https://news.gallup.com/poll/1645/guns.aspx. Accessed June 16, 2021.
- 54.Smith TW, Son J. General social survey final report: trends in gun ownership in the United States, 1972−2018. NORC at the University of Chicago. https://www.norc.org/PDFs/GSS%20Reports/GSS_Trends%20in%20Gun%20Ownership_US_1972-2014.pdf. Published March 2015. Accessed June 16, 2021. [Google Scholar]
- 55.Bond AE, Anestis MD. Firearm type and number: examining differences among firearm owning suicide decedents. Arch Suicide Res. In press. Online February 11, 2021. 10.1080/13811118.2021.1885536. [DOI] [PubMed] [Google Scholar]
- 56.Dahlberg LL, Ikeda RM, Kresnow M. Guns in the home and risk of a violent death in the home: findings from a national study. Am J Epidemiol. 2004;160(10):929–936. 10.1093/aje/kwh309. [DOI] [PubMed] [Google Scholar]
- 57.Hanlon TJ, Barber C, Azrael D, Miller M. Type of firearm used in suicides: findings from 13 states in the National Violent Death Reporting System, 2005−2015. J Adolesc Health. 2019;65(3):366–370. 10.1016/j.jadohealth.2019.03.015. [DOI] [PubMed] [Google Scholar]
- 58.Whitley E, Gunnell D, Dorling D, Smith GD. Ecological study of social fragmentation, poverty, and suicide. BMJ. 1999;319(7216):1034–1037. 10.1136/bmj.319.7216.1034. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 59.Kim D. The associations between US state and local social spending, income inequality, and individual all-cause and cause-specific mortality: the National Longitudinal Mortality Study. Prev Med. 2016;84:62–68. 10.1016/j.ypmed.2015.11.013. [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.