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. 2021 Oct 27;13(10):e19070. doi: 10.7759/cureus.19070

Table 2. Distribution of factors associated with COVID-19 breakthrough infections in HCWs (N=279)***.

*Prior to administration of the first dose of COVID-19 vaccine.

**Post-vaccination with at least one dose of vaccine.

***Excluding those HCWs who received only a dose of vaccine (n=46).

COVID-19: coronavirus disease 2019; HCWs: healthcare workers

Characteristic Total (N=279) Breakthrough infections (n=37) Unadjusted odds 95% CI p-Value
Vaccine type  
BBV152 154 (55.2%) 24 (15.6%) 1.5 (0.77, 3.3) 0.219
AZD1222 125 (44.8%) 13 (10.4%) 1
Age (years)  
<35 215 (77.1%) 31 (14.4%) 1 0.401
≥35 64 (22.9%)  6 (9.4%) 0.61 (0.24, 1.5)
Sex  
Male 178 (63.8%) 27 (15.2%) 1 0.271
Female 101 (36.2%) 10 (9.9%) 1.6 (0.7, 3.5)
HCW type        
Doctor 217 (77.8%) 32 (14.7%) 1 0.206
Other 62 (22.2%) 5 (8.1%) 0.5 (0.19, 1.4)
History of COVID-19 infection*  
Present 40 (14.3%) 3 (7.5%) 0.49 (0.14, 1.7) 0.319
Absent 239 (85.7%) 34 (14.2%) 1
Masking adherence**  
Always 190 (68.1%) 26 (13.7%) 1 0.851
Mostly/other 89 (31.9%) 11 (12.4%) 0.89 (0.42, 1.9)
Social distancing adherence**        
Always 172 (61.6%) 21 (12.2%) 1 0.315
Mostly/other 107 (38.4%) 16 (15.0%) 1.3 (0.63, 2.5)