Skip to main content
. 2021 Nov 21;13(11):1974. doi: 10.3390/pharmaceutics13111974

Figure 6.

Figure 6

In vivo experimental therapy using Z-ABD-mcDM1, ABD-Z-Z-mcDM1, and the controls Z-ABD, ABD-Z-Z, and BSA in PBS. Treatment was started at day 0 and continued weekly for 10 weeks or to the humane end point (xenograft volume over 1 cm3 or tumor ulcerated). (A) The average tumor volume of each group as a function of time ± SD. Curves were stopped when 30–33% of the mice in a group were euthanized. (B) The average mice weight in groups as a function of time ± SD. (C) The survival until euthanasia criteria of the xenografted mice. (D) The therapy output. * corresponds to significant difference (p < 0.05).