Table 2.
Protective effect of blackcurrant on diabetes-induced cardiac dysfunction.
| Characteristics | Cont. | T2DM | Vil.G | Bla.C | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LVEDV (mL) | 0.098 | ± | 0.013 | 0.185 | ± | 0.038 *** | 0.105 | ± | 0.012 ## | 0.121 | ± | 0.011 ## |
| LVESV (mL) | 0.013 | ± | 0.002 | 0.072 | ± | 0.020 *** | 0.018 | ± | 0.002 ### | 0.032 | ± | 0.009 ### |
| LVd Mass (g) | 0.109 | ± | 0.007 | 0.204 | ± | 0.040 *** | 0.106 | ± | 0.008 # | 0.111 | ± | 0.007 ## |
| LVIDd (mm) | 3.328 | ± | 0.134 | 4.017 | ± | 0.266 ** | 3.395 | ± | 0.126 ## | 3.609 | ± | 0.108 # |
| LVPWd (mm) | 1.038 | ± | 0.107 | 1.253 | ± | 0.107 ** | 0.893 | ± | 0.071 ## | 0.960 | ± | 0.050 ## |
Cont, control, db/m mice; T2DM, db/db mice, type 2 diabetes mellitus mice; Vil.G, db/db + vildagliptin 50 mg/kg/day, positive control, dipeptidyl peptidase-4 (DPP-4) inhibitor; Bla.C, db/db + blackcurrant 200 mg/kg/day; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVd Mass, left ventricular mass; LVIDd, left ventricular internal dimension in diastole; LVPWd, left ventricle posterior wall thickness. Data are shown as mean ± S.E. (n = 8 per group). ** p < 0.01, *** p < 0.001 vs. Cont; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. T2DM.