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. 2021 Nov 22;26(22):7045. doi: 10.3390/molecules26227045

Table 6.

Clinical features of the 26 TMAU patients involved in this study. Signs, symptoms, and pathological features listed are those most frequently observed in TMAU affected individuals, as well as several ones specific of particular cases.

ID Age Smell Description Intestinal Disorders Liver Diseases Age of Onset Drugs Supplements/Probiotics
1 9 Rotten fish / / 6 months / /
2 42 Rotten fish Colitis no 7/8 years no no
3 48 Genital fishy odour, body garbage odour, and scalp acid/sulphur odour Irritable colon no 10 years Eutirox, Prisma 50 no
4 Rotten fish
5 36 Rotten fish Moderate degree of dysbiosis no 2/3 years
6 71 Rotten fish Megacolon, anorectal stenosis, constipation, and congenital sacro-coccygeal malformation with fistulas / 2/3 years / /
7 38 Rotten fish / / 37 years Atazanavir, Abacavoir, and Lamivudin Riboflavin
8 45 Rotten fish / / 38 years Oral contraceptives /
9 21 Rotten fish no no 6/7 years no no
10 73 Rotten fish no no 63 years / no
11 51 Fish no no 2/3 years no no
12 20 Rotten fish no no 6 months no no
13 28 Fish no no After weaning no no
14 12 Rotten fish / / 5 years / /
15 31 Rotten fish, garbage, and garlic Moderate dysbiosis no 17 years / /
16 51 Rotten fish / / 44 years Medicinal herbs /
17 26 Rotten fish no no 14 years Psychotropic drugs and tranquilizers
18 48 Rotten fish, faecal odour Mild dysbiosis, slow oro-caecal transit no / /
19 52 Rotten fish Mild dysbiosis no 6 years / Flebinic
(carnitine-based supplement)
20 24 Rotten fish no no After weaning no Activated carbon
21 38 Rotten fish no no 34 years no no
22 13 Rotten fish no no 10 years no no
23 28 Rotten fish no no 28 years no no
24 27 Rotten fish, faecal odour, rot, and sulphur Mild dysbiosis no 4 years no no
25 47 Rotten fish / / 39 years / /
26 71 Rotten fish / / 2/3 years / Assumption of a.a.