Table 4.
Effects of the PVA concentration on the size, polydispersity (PDI), loading content (LC), entrapment efficiency (EE) and functionality of the resulting HbNPs.
| Sample ID | Hb (mg mL−1) |
PLGA (mg mL−1) |
PVA (%) |
Size (nm) | PDI | LC (%) | EE (%) | Functional |
|---|---|---|---|---|---|---|---|---|
| HbNPs-22 | 50 | 5 | 0.2 | 470.0 | 0.199 | 15.2 | 37.7 | Yes |
| HbNPs-23 | 50 | 5 | 0.5 | 379.0 | 0.175 | 13.9 | 39.8 | Yes |
| HbNPs-9 | 50 | 5 | 1.0 | 312.0 | 0.155 | 18.7 | 42.9 | Yes |
| HbNPs-24 | 50 | 5 | 2.0 | 253.7 | 0.160 | 9.7 | 20.5 | Yes |
| HbNPs-25 | 75 | 3 | 0.2 | 357.5 | 0.317 | 25.2 | 31.6 | Yes |
| HbNPs-26 | 75 | 3 | 0.5 | 344.5 | 0.172 | 26.9 | 40.7 | Yes |
| HbNPs-13 | 75 | 3 | 1.0 | 369.7 | 0.241 | 29.0 | 41.5 | Yes |
| HbNPs-27 | 75 | 3 | 2.0 | 349.6 | 0.258 | 20.8 | 27.3 | Yes |
| HbNPs-28 | 75 | 5 | 0.2 | 484.4 | 0.427 | 26.7 | 39.4 | Yes |
| HbNPs-29 | 75 | 5 | 0.5 | 352.1 | 0.165 | 24.9 | 41.9 | Yes |
| HbNPs-14 | 75 | 5 | 1.0 | 331.4 | 0.174 | 21.7 | 38.0 | Yes |
| HbNPs-30 | 75 | 5 | 2.0 | 307.4 | 0.249 | 18.3 | 19.7 | Yes |