Figure 7.
Effect of time restricted feeding on clock gene mRNA expression in the colonic mucosa. (A) Arntl and (B) Reverbα mRNA expression in the mouse distal colonic mucosa of control mice fed a TRF diet (Ctrl RF), jetlagged mice fed ad libitum (JL AL) and jetlagged mice fed a TRF diet (JL RF) (N = 8 mice per time point per group). The fitted cosine curve determined by cosinor analysis (period = 24 h) are shown in Ctrl RF, JL AL and JL RF mice. The dark phase is shaded grey. Statistics: Non-linear regression (Proc NLIN). p-values refer to probability values for the best fitting cosine curve.