Table 1.
Baseline Demographic Characteristics
| Characteristic | Total Cohort (N = 750) | Operated (n = 566) | Inoperable (n = 96) | Operable/No Surgery (n = 88) | P Value and Significance |
|---|---|---|---|---|---|
| Age, median [Q1-Q3], y | 59 [46-69] | 57 [44-67] | 67 [56-74] | 66 [52-73] | < .001a,b,c |
| Sex (% male) | 50.8 | 52.7 | 40.6 | 50.0 | .094 |
| Race/ethnicity | .026a,c | ||||
| Non-Hispanic white | 492 (65.6%) | 373 (65.9%) | 65 (67.7%) | 54 (61.4%) | |
| Non-Hispanic black | 168 (22.4%) | 120 (21.2%) | 19 (19.8%) | 29 (33%) | |
| Hispanic | 44 (5.9%) | 40 (7.1%) | 4 (4.2%) | 0 (0%) | |
| Other | 46 (6.1%) | 33 (5.8%) | 8 (8.3%) | 5 (5.7%) | |
| BMI, median [Q1-Q3], kg/m2 | 29.7 [25.8-35.9] | 30.4 [26.1-36.3] | 27.3 [23.8-34.1] | 30.3 [26.4-35.3] | .006a,b |
| 6MWD median [Q1-Q3], m | 329 [235-400] n = 374 | 334 [235-406] n = 253 | 321 [244-376] n = 64 | 303 [228-389] n = 57 | .390 |
| WHO functional class I/II/III/IV, % | 2/22/63/13 | 1/21/65/12 | 3/23/56/18 | 6/26/59/9 | .058 |
| Median time from symptom onset to suspicion of CTEPH, mo | 10.1 [3.0-26.1] | 12.1 [4.0-29.4] | 7.0 [2.0-15.1] | 6.0 [2.0-17.7] | < .001a,b,c |
6MWD = 6-min walk distance; CTEPH = chronic thromboembolic pulmonary hypertension; PTE = pulmonary thromboendarterectomy; Q1-Q3 = first/third quartiles; WHO = World Health Organization.
a
Comparison among three groups, P < .05 statistically significant.
b
Between-group (Inoperable vs Operated) comparisons, P < .017 statistically significant.
c
Between-group (Operable/No Surgery vs Operated) comparisons, P < .017 statistically significant.