Rationale: Malnutrition in critically ill COVID-19 and its long-term effects are not well known(1). NUTRICOVID study aims to describe 1-yr evolution of nutritional, functional status, and health-related quality of life (HRQoL) of COVID-19 survivors post-discharge.
Methods: A multicenter, ambispective, observational study is being conducted in 16 hospitals of Madrid (Spain) with ICU COVID-19 survivors of the 1st outbreak (March-June 2020). A descriptive interim analysis at 3 months post-discharge was performed (STATA v.14) including nutritional status (weight, MUST), functional status (SARC-F, Barthel), medical nutritional treatment (MNT) and HRQoL (EQ-5D) at discharge and at 3 months.
Results: A total of 199 patients were included: 70% male, mean age (SD) 61 (10) years; average (SD) weight loss during hospital stay 16% (8%). At discharge, 83% and 87% of patients were at high risk of malnutrition and sarcopenia, 81% were moderate-highly dependent, and 70 patients received MNT. At 3 months, the average (SD) weight gain was 8% (9%), 17% and 34% of patients were still at high risk of malnutrition and sarcopenia, but 63% were independent. 18 patients were still on MNT. The median EQ-VAS (IQR) at discharge was 40 (25-50), and improved to 60 (50-75) at 3 months. Distribution of patients with moderate to extreme problems/feelings according to EQ-5D was:
| At discharge (N=178) | After 3-months (N=165) | |
|---|---|---|
| Mobility | 72% (128) | 25% (41) |
| Self-care | 52% (93) | 11% (18) |
| Usual activities | 77% (137) | 30% (49) |
| Pain/discomfort | 63% (113) | 36% (59) |
| Anxiety/depression | 42% (75) | 24% (40) |
Conclusion: This analysis evidences the favorable improvement on nutritional and functional status and HRQoL experienced in ICU COVID-19 survivors from hospital discharge to 3 months afterwards.
References:
1. Cawood AL et al. A Review of Nutrition Support Guidelines for Individuals with or Recovering from COVID-19 in the Community. Nutrients. 2020;12(11).
Disclosure of Interest: None declared.
LB-041