Table 2.
Association between MX1 score and overall survival or recurrence-free survival using a univariate model or multivariate models controlling for patient age, clinical stage, disease site, comorbidities, HPV status, smoking history, and CD4+ (middle) or CD8+ TILs (bottom)
| MX1 Group | Overall Survival (OS) | Recurrence-Free Survival (RFS) | ||
|---|---|---|---|---|
| Univariate model | HR (95% CI)a | P-value | HR (95% CI) | P-value |
| MX1 score (1 unit increase) | 1.00 (0.99, 1.02) | 0.12 | 1.01 (0.99, 1.02) | 0.35 |
| MX1-high (≥ 41) | 1.97 (1.11, 3.48) | 0.02 | 1.49 (0.73, 3.06) | 0.28 |
| Multivariate model (CD4+) | HR (95% CI) | P-value | HR (95% CI) | P-value |
| MX1 score (1 unit increase) | 1.01 (1.00, 1.03) | 0.14 | 1.00 (0.99, 1.03) | 0.43 |
| MX1-high (≥ 41) | 1.96 (1.02, 3.74) | 0.04 | 1.73 (0.77, 3.87) | 0.18 |
| Multivariate model (CD8+) | HR (95% CI) | P-value | HR (95% CI) | P-value |
| MX1 score (1 unit increase) | 1.00 (0.99, 1.02) | 0.66 | 1.00 (0.98, 1.02) | 0.99 |
| MX1-high (≥ 41) | 1.30 (0.68, 2.48) | 0.42 | 1.25 (0.56, 2.78) | 0.58 |
aAbbreviations: HR: hazard ratio; CI: confidence interval.