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. 2021 Nov 30;97(22):e2223–e2235. doi: 10.1212/WNL.0000000000012919

Figure 3. Partitioned Genetic Correlations Between Lipoprotein Subfraction Measures and Migraine (Any Migraine, Migraine With Aura, and Migraine Without Aura) According to 11 Functional Categories Using Linkage Disequilibrium Score Regression.

Figure 3

Colors represent the magnitude of genetic correlation between lipoprotein subfraction measures and migraine using linkage disequilibrium score regression: red for positive genetic correlation and blue for negative genetic correlation. Numbers represent the genetic correlation at nominal significance level (p < 0.05). *Significant genetic correlation after controlling for multiple testing (p < 0.05/[19 × 11]). ApoA1 = apolipoprotein A1; ApoB = apolipoprotein B100; HDLP = high-density lipoprotein particles; HDLZ = high-density lipoprotein mean particle size; L-HDLP = large high-density lipoprotein particles; L-LDLP = large low-density lipoprotein particles; L-TRLP = large triglyceride-rich lipoprotein particles; LDLP = low-density lipoprotein particles; LDLZ = low-density lipoprotein mean particle size; M-HDLP = medium high-density lipoprotein particles; M-LDLP = medium low-density lipoprotein particles; M-TRLP = medium triglyceride-rich lipoprotein particles; MA = migraine with aura; MO = migraine without aura; S-HDLP = small high-density lipoprotein particles; S-LDLP = small low-density lipoprotein particles; S-TRLP = small triglyceride-rich lipoprotein particles; TRLP = triglyceride-rich lipoprotein particles; TRLZ = triglyceride-rich lipoprotein mean particle size; VL-TRLP = very large triglyceride-rich lipoprotein particles; VS-TRLP = very small triglyceride-rich lipoprotein particles.