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Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine logoLink to Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
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. 2021 Oct;25(10):1211. doi: 10.5005/jp-journals-10071-23982

Reanalyzing the Mortality Analysis of COVID-19 Deaths in a Tertiary Care Center in India

Abhijeet Anand 1,, Reecha Panghal 2, Paridhi Kaler 3, Saurabh Saigal 4, Rajesh Panda 5, Saiteja Kodamanchili 6, Krishnkant Bhardwaj 7, TB Gowthaman 8
PMCID: PMC8645815  PMID: 34916762

Abstract

How to cite this article: Anand A, Panghal R, Kaler P, Saigal S, Panda R, Kodamanchili S, et al. Reanalyzing the Mortality Analysis of COVID-19 Deaths in a Tertiary Care Center in India. Indian J Crit Care Med 2021; 25(10):1211.


Sir,

Recently, one of the most awaited publications by the premier government medical institute of our country, titled “Clinicoepidemiological Features and Mortality Analysis of Deceased Patients with COVID-19 in a Tertiary Care Center”, was a very delightful read.1 All the intensivists of India look up to this institute for regular guidelines of management of COVID-19. It is a very informative and learning piece analyzing mortality among the patients admitted to one of the (intensive care units) ICU of this center.

When compared with other similar studies across the globe, this paper does not provide supplementary data that could have answered questions like how many of the admitted patients were intubated in total and what was the mortality rate among the subgroup who were intubated.2,3 Rather a retrospective approach of data representation has been employed, which tells that among the total 247 deceased patients, 24.2% were intubated and 30.3% of total deceased were intubated within 24 hours. Even this representation does not throw light on how many patients of total 654 patients were intubated during their ICU stay. The policy guiding intubation of patients should also be specified as if it was decided by the intensivist on duty or by any fixed institutional criteria.

The incidence of pulmonary embolism (PE) among the deceased in the original paper is 2.8%, which is quite less than reported by Mahmoud et al. in a meta-analysis who reported the overall PE rate in ICU to be 19%, and on autopsy, 22% of deceased patients were found to have PE in COVID-19.4 The question that remains unanswered is how were those patients, who died in this published paper, diagnosed with PE. The diagnosis of PE was a clinical diagnosis or radiological diagnosis or by autopsy should have been specified. If the incidence of PE is so less than what was the antithrombotic practice of the institute as this piece of information can help to save many lives.

Orcid

Abhijeet Anand https://orcid.org/0000-0001-6498-5388

Reecha Panghal https://orcid.org/0000-0002-8695-5371

Paridhi Kaler https://orcid.org/0000-0002-3100-5133

Saurabh Saigal https://orcid.org/0000-0002-2364-2271

Rajesh Panda https://orcid.org/0000-0001-7123-876X

Saiteja Kodamanchili https://orcid.org/0000-0003-1033-0321

Krishnkant Bhardwaj https://orcid.org/0000-0002-2207-0654

Gowthaman TB https://orcid.org/0000-0002-0301-3793

Footnotes

Source of support: Nil

Conflict of interest: None

References

  • 1.Kumar R, Malhotra R, Guleria R, Wig N, Patel N, Trikha A, et al. Clinicoepidemiological features and mortality analysis of deceased patients with COVID-19 in a tertiary care center. Indian J Crit Care Med. 2021;25(6):622–628. doi: 10.5005/jp-journals-10071-23848. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Grasselli G, Greco M, Zanella A, Albano G, Antonelli M, Bellani G, et al. Risk factors associated with mortality among patients with COVID-19 in intensive care units in Lombardy, Italy. JAMA Intern Med. 2020;180(10):1345. doi: 10.1001/jamainternmed.2020.3539. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Wang Y, Lu X, Li Y, Chen H, Chen T, Su N, et al. Clinical course and outcomes of 344 intensive care patients with COVID-19. Am J Respir Crit Care Med. 2020;201(11):1430–1434. doi: 10.1164/rccm.202003-0736LE. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Malas MB, Naazie IN, Elsayed N, Mathlouthi A, Marmor R, Clary B. Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: a systematic review and meta-analysis. EClinicalMedicine. 2020;29–30:100639. doi: 10.1016/j.eclinm.2020.100639. [DOI] [PMC free article] [PubMed] [Google Scholar]

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