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. 2021 Nov 15;24(12):103449. doi: 10.1016/j.isci.2021.103449

Figure 4.

Figure 4

SMS1/SMS2 deficiency-mediated lipogenesis, inflammation, fibrosis, and tumorigenesis gene expression

(A) Heatmap for genes related to lipogenesis, inflammation, fibrosis, and tumorigenesis in WT vs. Sms1/Sms2 KO mouse hepatocytes.

(B) Real-time PCR for related genes.

(C and D) Western blot for liver TGFβ1, collagen 1α1, PDGFRα, and PDGFRβ, as well as quantifications.

(E) Inflammation array analysis. Inflammatory cytokines were measured by using the Mouse Inflammation Array C1 kit (RayBiotch). Each measurement was performed in duplicate.