TABLE 1.
Non‐vaccinated (a) (n = 48) | Vaccinated | p value | ||
---|---|---|---|---|
1 vaccine dose (b) (n = 31) | 2 vaccine doses (c) (n = 317) | |||
Age, mean (SD), year a | 87.2 (9.2) | 85.1 (9.2) | 87.6 (9.2) | .22 |
Sex, n (%) b | ||||
Female | 35 (72.9) | 25 (80.7) | 252 (79.5) | .56 |
Male | 13 (27.1) | 6 (19.3) | 65 (20.5) | |
Charlson index (median, IGR) [range] a |
6.0 (5.0–7.0) 2–15 |
6.0 (5.0–8.0) 3–15 |
6.0 (5.0–7.0) 2–15 |
.41 |
Prior SARS‐CoV−2 positive RT‐qPCR, n (%) b | 5 (10.4) | 3 (9.7) | 43 (13.6) | .82 |
Positive RT‐qPCR during the SARS‐CoV‐2 B.1.1.7 outbreak, n (%) b | 21 (43.7) | 10 (32.3) | 72 (22.7) |
.0059 .005 (a vs c) |
N‐protein IgG >0.8 signal to cutoff ratio, n (%) c | 5 (20.0) | 5 (17.9) | 38 (14.0) | .57 |
RBD‐IgG level, AU/ml, median (IQR) a |
n = 26 2 (1–415) |
n =28 534.00 (201.50; 2166.50) |
n =271 1,522.00 (444.00; 5389.00) |
.000001 .001 (a vs b) .01 (a vs c) .08: (b vs c) |
COVID‐19–related deaths during the SARS‐CoV‐2 B.1.1.7 outbreak, n (%) c | 5 (10.4) | 2 (6.4) | 3 (0.9) |
.0007 .004 (a vs c) |
Analysis using Kruskal‐Wallis test.
Analysis using chi‐square test.
Analysis using Fisher's exact test.