FIGURE 5.

Sera of mice vaccinated with mCuMV_TT‐RBM efficiently recognize SARS‐CoV‐2 Variants of Concern (VoC). A, RBD‐specific IgG titers for the group vaccinated with mCuMV_TT‐RBM measured by ELISA OD₄₅₀ measured on day 42. B, Log₁₀OD₅₀ of RBD‐specific IgG titers for the group vaccinated with mCuMV_TT‐RBM (data from A). ELISA plates were coated with either RBD_wildtype, RBD_K417N, RBD_E484K, RBD_N501Y, RBD_{K417N/E484K/N501Y,} or RBD_L452R/E484Q. Statistical analysis (mean ±SEM) using one‐way ANOVA, n=5. One representative of 2 similar experiments is shown. The value of p<0.05 was considered statistically significant (*p<0.01, **p<0.001, ***p<0.0001)