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. 2021 Nov 29;26(23):7228. doi: 10.3390/molecules26237228

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Bioactivity screening results for cytotoxic inhibition activities of compounds 1–28. (p, positive drug irinotecan, HepG2, 0.6 μM; A549, 1.0 μM; MCF-7, 0.9 μM; ea, EtOH crude extracts 25 μg/mL). (B) The dose–inhibition rate curves for active compounds and their IC₅₀ values. (a: data of HepG2, b: data of A549, c: data of MCF-7).