Table 2.

The RMSF value of the catalytic center of the Mpro-DRV/LPV/NFV/RBV/RTV complex and Mpro_apo.

Complex	His41 (nm)	Gly145 (nm)
Mpro_apo	0.128 ± 0.009	0.090 ± 0.007
Darunavir	0.070 ± 0.010	0.056 ± 0.007
Lopinavir	0.067 ± 0.012	0.063 ± 0.010
Nelfinavir	0.057 ± 0.008	0.057 ± 0.012
Ribavirin	0.072 ± 0.009	0.067 ± 0.009
Ritonavire	0.113 ± 0.013	0.066 ± 0.011