In this article, we found that there are some mistakes in Figures 3, 5, 6, and the correct pictures are shown below. We would like to publish this Erratum to reflect changes. The authors express regrets for these mistakes.
Figure 3.
Runx2 is a target of miR-217 in glioma cells. A. Runx2 has binding sequences for miR-217 at position (3386-3393). B. The luciferase activity of U87 cells was determined after co-transfection with the miR-217 mimics or miR-NC and wide-type or mutant-type report plasmid. C. qRT-PCR was performed to detect the expression of Runx2 in U87 cells transfected with miR-217 mimics or miR-NC. The GAPDH was used as an internal control. D. Western blotting analyzed the protein level of Runx2 in U87 cells transfected with miR-217 mimics or miR-NC. The GAPDH was used as an internal control. *P<0.05, **P<0.01 versus miR-NC.
Figure 5.
Downregulation of Runx2 exhibited similar effect with miR-217 overexpression in glioma cells. A and B. Runx22 expression on mRNA level and protein level were measured in U87 cells transfected with si-Runx2 or si-NC by qRT-PCR and western blot, respectively. GAPDH was used as an internal control. C-F. Cell proliferation, colony formation, migration and invasion were determined in U87 cells after transfected with si-Runx2 or si-NC. *P<0.05, **P<0.01 versus si-NC.
Figure 6.
Overexpression of Runx2 rescues the effects of miR-217 in glioma cells. A and B. Runx2 expression on mRNA level and protein level in U87 cells co-transfected with Runx2 overexpression plasmid and miR-217 mimic or miR-NC by qRT-PCR and western blot, respectively. GAPDH was used as an internal control. C-F. Cell proliferation, colony formation, migration and invasion were determined in U87 cells transfected with miR-217 mimic with/without Runx2 overexpression plasmid. *P<0.05, **P<0.01 versus miR-217.