Neuro Oncology Advances Brain Metastases Supplement
Launch Date: November 26, 2021
Expiration Date: November 26, 2022
Time to Complete Activity: 6.0 Hours
This activity is jointly provided by Global Education Group and Society for Neuro-Oncology.
This activity is supported by an educational grant from Novocure, Inc. and Seagen Inc.
Target Audience
The educational design of this activity addresses the need of Researchers, Neuro-Oncologists, Neurosurgeons Nurse Practitioners, and Allied Health Professionals involved in the management of CNS brain tumors.
Statement of Need/Program Overview
Using a multidisciplinary collaborative effort from researchers and clinicians, the Society for Neuro-Oncology Journal Supplement’s purpose is to provide superior publications dedicated to educating all those interested in advancing the outcomes for patients with CNS cancers.
Educational Objectives
After completing this activity, the participant should be better able to:
Explain advances in neurosurgical interventions used in patients with metastatic brain tumors.
Identify indications for laser interstitial thermal therapy in treating metastases to the brain.
Describe advances in radiation therapy for the treatment of intracranial metastases.
Summarize current targeted therapy options for brain and leptomeningeal metastases.
Discuss the role for immunotherapy in managing patients with intracranial metastases.
Outline potential therapy induced neurological morbidities.
Recognize approaches used to preserve patient neuro-cognitive function.
Describe treatment challenges associated with the tumor microenvironment.
Explain the impact of the blood-tumor barrier on the intracranial penetrance of systemic therapies.
Discuss animal models of brain metastasis used to evaluate novel therapies.
|
Chris E. Adkins, PharmD
Department of Pharmaceutical Sciences, School of Pharmacy South University Savannah, GA, USA |
Yssabela M. Cabuyao, BS Candidate
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
|
Manish K. Aghi, MD, PhD
Department of Neurosurgery University of California San Francisco San Francisco, CA, USA |
Bryan D. Choi, MD PhD
Department of Neurosurgery Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
|
Carey K. Anders, MD
Department of Medicine, Division of Medical Oncology Duke Center for Brain and Spine Metastasis Duke Cancer Institute Durham, NC, USA |
Caroline Chung, MD, MSc
Department of Radiation Oncology University of Texas MD Anderson Cancer Center Houston, TX, USA |
|
Tasneem A. Arsiwala, MPharm
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
Michael A. Davies, MD, PhD
Department of Melanoma Medical Oncology The University of Texas MD Anderson Cancer Center Houston, TX, USA |
|
Sonikpreet Aulakh, MD
Department of Cancer Cell Biology, School of Medicine West Virginia University Morgantown, WV, USA |
Krutika Deshpande, PhD
Department of Neurological Surgery Keck School of Medicine University of Southern California Los Angeles, CA, USA |
|
Gene H. Barnett, MD, MBA
Department of Neurosurgery Cleveland Clinic & Case Comprehensive Cancer Center Cleveland, OH, USA |
Leland E. Earp, BS
Department of Cancer Cell Biology, School of Medicine, West Virginia University Morgantown, WV, USA |
|
Anna S. Berghoff, MD, PhD
Division of Oncology, Department of Medicine I, Medical University of Vienna Vienna, Austria |
Mahsa Eskian, MD
Division of Neuromuscular Medicine, Department of Neurology Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
|
Kathryn E. Blethen, BS
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
Peter E. Fecci, MD PhD
School of Medicine, Department of Neurosurgery Duke University Medical Center Durham, NC, USA |
|
Adrienne Boire, MD, PhD
Human Oncology and Pathogenesis Program Brain Tumor Center Department of Neurology Memorial Sloan Kettering Cancer Center New York, NY, USA |
Ross A. Fladeland, BS
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
|
Priscilla K. Brastianos, MD
Division of Hematology/Oncology, Department of Medicine Division of Neuro-Oncology, Department of Neurology Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
Scott R. Floyd, MD, PhD
Department of Radiation Oncology Duke University School of Medicine Durham, NC, USA |
|
Paul David Brown, MD
Department of Radiation Oncology Mayo Clinic Rochester, MN, USA |
Morgan J. Glass, BS Candidate
Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University Morgantown, WV, USA |
|
Leeann B. Burton, MD
Division of Neuromuscular Medicine, Department of Neurology Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
Vinai Gondi, MD
Northwestern Medicine Cancer Center Warrenville and Proton Center Warrenville, IL, USA |
|
Yssabela M. Cabuyao, BS Candidate
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
Matthew M. Grabowski, MD
Department of Neurosurgery Cleveland Clinic & Case Comprehensive Cancer Center Cleveland, OH, USA |
|
Amanda C. Guidon, MD
Division of Neuromuscular Medicine, Department of Neurology Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
Michael W. Parsons, PhD
Pappas Center for Neuro-Oncology Department of Psychiatry Massachusetts General Hospital Boston, MA, USA |
|
Mustafa Khasraw, MD
Duke Brain and Spine Metastases Center Duke University Durham, NC, USA |
Katherine B. Peters, MD, PhD
Preston Robert Tisch Brain Tumor Center Department of Neurosurgery Duke University Medical Center Durham, NC, USA |
|
Brooke N. Kielkowski, PharmD Candidate
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
Erqi Pollom, MD, MS
Assistant Professor Department of Radiation Oncology Stanford Cancer Institute Palo Alto, CA, USA |
|
Priya Kumthekar, MD
Department of Neurology Malnati Brain Tumor Institute at the Robert H. Lurie Comprehensive Cancer Center Northwestern University Feinberg School of Medicine Chicago, IL, USA |
Matthias Preusser, MD
Professor Division of Oncology, Department of Medicine I Medical University of Vienna Vienna, Austria |
|
Paul R. Lockman, PhD
Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
Trenton Pritt, BS Candidate
Bachelor of Science Student Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
|
Jacquelyn Meyer, BS Candidate
Bachelor of Science Student University of Wisconsin-Madison Madison, WI, USA |
Kerry L. Reynolds, MD
Division of Oncology, Department of Medicine Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
|
Lauritz Miarka, MD Candidate
MD Student Brain Metastasis Group, Molecular Oncology Programme Spanish National Cancer Research Centre (CNIO) Madrid, Spain |
Chantal Saberian, MD
Department of Melanoma Medical Oncology The University of Texas MD Anderson Cancer Center Houston, TX, USA |
| Nathaniel J. Myall, MD, MS Clinical Assistant Professor Division of Oncology, Department of Medicine Stanford Cancer Institute Palo Alto, CA, USA |
Sarah Sammons, MD
Assistant Professor Department of Medicine, Division of Medical Oncology Duke Cancer Institute Durham, NC, USA |
|
Brian V. Nahed, MD, MSc
Department of Neurosurgery Massachusetts General Hospital Boston, MA, USA |
Ugur Sener, MD
Assistant Professor Department of Neurology West Virginia University School of Medicine Morgantown, WV, USA |
|
Josh Neman, PhD
Department of Neurological Surgery, Physiology and Neuroscience USC Brain Tumor Center Norris Comprehensive Cancer Center Keck School of Medicine University of Southern California Los Angeles, CA, USA |
Helen A. Shih, MD, MS, MPH
Department of Radiation Oncology Massachusetts General Hospital Boston, MA, USA |
|
Patrick Ng, BS, BA
Department of Neurosurgery Massachusetts General Hospital Harvard Medical School Boston, MA, USA |
David B. Schultz, MD, PhD
Radiation Medicine Program, Princess Margaret Cancer Centre University Health Network Toronto, ON, Canada |
| Dhruvi M. Panchal, MPharm Graduate Research Assistant Department of Basic Pharmaceutical Sciences, School of Pharmacy Department of Chemical and Biomedical Engineering Benjamin M. Statler College of Engineering and Mineral Resources West Virginia University Morgantown, WV, USA |
Scott G. Soltys, MD
Assistant Professor Department of Radiation Oncology Stanford Cancer Institute Palo Alto, CA, USA |
|
Paul Sperduto, MD
Minneapolis Radiation Oncology Minneapolis, MN, USA |
Heather A. Wakelee, MD
Division of Oncology, Department of Medicine Stanford Cancer Institute Palo Alto, CA, USA |
|
Samuel A. Sprowls, BS
Postdoctoral Fellow Department of Basic Pharmaceutical Sciences, School of Pharmacy West Virginia University Morgantown, WV, USA |
Jianbo Wang, MD, PhD
Department of Genitourinary Malignancies University of Texas M.D. Anderson Cancer Center Houston, TX, USA |
|
Ethan S. Srinivasan, BS
Medical Student Duke Brain and Spine Metastases Center School of Medicine Duke University Durham, NC, USA. |
Jeffrey S. Wefel, PhD
Department of Neuro-Oncology Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston, TX, USA |
|
Adriane Steindl, MD
Division of Oncology, Department of Medicine I Medical University of Vienna Vienna, Austria |
Frank Winkler, MD, PhD
Neurology Clinic and National Center for Tumor Diseases University Hospital Heidelberg Clinical Cooperation Unit Neuro-oncology German Cancer Consortium German Cancer Research Center Heidelberg, Germany |
|
Hussein A. Tawbi, MD, PhD
Professor Department of Melanoma Medical Oncology University of Texas M.D. Anderson Cancer Center Houston, TX, USA |
Helena Yu, MD
Department of Medicine-Oncology Memorial Sloan Kettering Cancer Center New York, NY, USA |
|
Manuel Valiente, PhD
Brain Metastasis Group, Molecular Oncology Programme Spanish National Cancer Research Centre (CNIO) Madrid, Spain |
Gelareh Zadeh, MD, PhD
Division of Neurosurgery, University Health Network University of Toronto MacFeeters-Hamilton Center for Neuro-Oncology Princess Margaret Cancer Center Toronto, ON, Canada |
|
Amanda E. D.Van Swearingen, PhD
Postdoctoral Research Associate Duke Center for Brain and Spine Metastasis Duke Cancer Institute Durham, NC, USA |
Jeffrey A. Zuccato, MD
Division of Neurosurgery, University Health Network University of Toronto MacFeeters-Hamilton Center for Neuro-Oncology Princess Margaret Cancer Center Toronto, ON, Canada |
Physician Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Society for Neuro-Oncology. Global is accredited by the ACCME to provide continuing medical education for physicians.
Physician Credit Designation
Global Education Group designates this enduring material for a maximum of 6.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Term of Offering
This activity was released on November 26, 2021 and is valid for one year. Requests for credit must be made no later than November 26, 2022.
Global Contact Information
For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.
Fee Information& Refund/Cancellation Policy
There is no fee for this educational activity.
Instructions to Receive Credit
In order to receive credit for this activity, the participant must:
Read the entire publication, including the CME information
Score 70% or better on the posttest
Complete the activity evaluation
Following online completion of the posttest and evaluation, a certificate of participation will be available for immediate download.
Technology Support
For any technical issues with the articles, please submit an enquiry via https://academic.oup.com/journals/pages/help/email_customer_services/general_customer_enquiry. For any technical issues with the posttest, evaluation, or your CME certificate, please contact melesa@soc-neuro-onc.org.
System Requirements
Browser Compatibility
The Oxford Academic website is optimized for use with currently supported, secure versions of these browsers: Chrome, Firefox, Internet Explorer, and Safari. It can be accessed using older versions, but some features may not function properly. Please check your browser or contact your organization’s IT department for details of any browser updates available.
The Oxford Academic website uses third-party plug-in software to display certain types of content. The third-party software may have features that are not supported by all browsers. Where possible, Oxford University Press will work with the third party to address browser-specific issues.
PC
Microsoft Windows 2000 SE or above.
Flash Player Plugin (v7.0.1.9 or greater)
Internet Explorer (v5.5 or greater), or Firefox
Adobe Acrobat Reader*
MAC
MAC OS 10.2.8
Flash Player Plugin (v7.0.1.9 or greater)
Safari
Adobe Acrobat Reader*
Internet Explorer is not supported on the Macintosh.
*Required to view printable (PDF) version of the lesson.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Society for Neuro-Oncology do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Disclosure of Conflicts of Interest
Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.
All relevant financial relationships have been mitigated.
All individuals in control of content have the following relevant financial relationships with ineligible companies:
| The faculty/authors reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity: | ||
| Name of Author | Role | Reported Financial Relationship |
| Chris E. Adkins | Author | Nothing to disclose |
| Manish K. Aghi | Author | Nothing to disclose |
| Carey K. Anders | Author | Consulting Fee (e.g., Advisory Board): Genentech, Eisai, IPSEN, Seattle Genetics, Astra Zeneca, Novartis, Immunomedics, Elucida, Athenex Contracted Research: PUMA, Lilly, Merck, Seattle Genetics, Nektar, Tesaro, G1-Therapeutics, ZION, Novartis, Pfizer |
| Tasneem A. Arsiwala | Author | Nothing to disclose |
| Sonikpreet Aulakh | Author | Consulting Fee (e.g., Advisory Board): TEMPUS Speakers’ Bureau: TEMPUS |
| Gene H. Barnett | Author | Consulting Fee (e.g., Advisory Board): Monteris Medical |
| Anna S. Berghoff | Author | Consulting Fee (e.g., Advisory Board): Daiichi Sankyo Contracted Research: Daiichi Sankyo, Roche Other (Describe): Travel support from Roche, Amgen and AbbVie |
| Kathryn E. Blethen | Author | Nothing to disclose |
| Adrienne Boire | Author | Other (Describe): Evren Technologies (scientific advisory board - unpaid), Patents (inventor) via Sloan Kettering Institute |
| Priscilla K. Brastianos | Author | Consulting Fee (e.g., Advisory Board): Pfizer, ElevateBio, Dantari, SK Life Sciences, Sintetica, Voyager Therapeutics Contracted Research: Merck, Eli Lilly, BMS, Mirati Honoraria: Pfizer |
| Paul David Brown | Author | Nothing to disclose |
| Leeann B. Burton | Author | Contracted Research: Support to learn about drug development paid to Massachusetts General Hospital by Biogen. |
| Yssabela M. Cabuyao | Author | Nothing to disclose |
| Bryan D. Choi | Author | Nothing to disclose |
| Caroline Chung | Author | Contracted Research: Siemens Healineers, Raysearch Laboratories |
| Michael A. Davies | Author | Consulting Fee (e.g., Advisory Board): Roche/Genentech, Array, Pfizer, Novartis, BMS, GSK, Sanofi-Aventis, Vaccinex, Apexigen, ABM Therapeutics Contracted Research: Roche/Genentech, GSK, Sanofi-Aventis, Array, Pfizer, Oncothyreon |
| Krutika Deshpande | Author | Nothing to disclose |
| Leland E. Earp | Author | Nothing to disclose |
| Mahsa Eskian | Author | Nothing to disclose |
| Peter E. Fecci | Author | Consulting Fee (e.g., Advisory Board): Monteris Medical Contracted Research: Monteris Medical Honoraria: Monteris Medical |
| Ross A. Fladeland | Author | Nothing to disclose |
| Scott R. Floyd | Author | Nothing to disclose |
| Morgan J. Glass | Author | Nothing to disclose |
| Vinai Gondi | Author | Nothing to disclose |
| Matthew M. Grabowski | Author | Nothing to disclose |
| Amanda C. Guidon | Author | Consulting Fee (e.g., Advisory Board): Momenta, Alexion, Ra pharmaceuticals Contracted Research: Momenta Pharma |
| Mustafa Khasraw | Author | Consulting Fee (e.g., Advisory Board): J&J Contracted Research: AbbVie, BMS Honoraria: Jax lab for genomic research |
| Brooke N. Kielkowski | Author | Nothing to disclose |
| Priya Kumthekar | Author | Consulting Fee (e.g., Advisory Board): Janssen, Orbus Therapeutics, Novocure, Celularity, SDP Oncology, Biocept, Affinia, Sintetica, Angiochem Other (Describe): Data Safety Monitoring Committee: Berg Oncology |
| Paul R. Lockman | Author | Nothing to disclose |
| Jacquelyn Meyer | Author | Nothing to disclose |
| Lauritz Miarka | Author | Nothing to disclose |
| Nathaniel J. Myall | Author | Honoraria: Remedy Health Media |
| Brian V. Nahed | Author | Consulting Fee (e.g., Advisory Board): Robeaute |
| Josh Neman | Author | Nothing to disclose |
| Patrick R. Ng | Author | Nothing to disclose |
| Dhruvi M. Panchal | Author | Nothing to disclose |
| Michael W. Parsons | Author | Consulting Fee (e.g., Advisory Board): Agios, Inc, Gamaka Bio |
| Katherine B. Peters | Author | Consulting Fee (e.g., Advisory Board): Vivacitas Oncology, Sapience Contracted Research: Servier, AbbVie, Agios, Biomimetix Honoraria: Eisai-Honoraria for educational event |
| Erqi Pollom | Author | Contracted Research: Genentech |
| Matthias Preusser | Author | Consulting Fee (e.g. Advisory Board): Bayer, Bristol-Myers Squibb, Novartis, Gerson Lehrman Group (GLG), CMC Contrast, GlaxoSmithKline, Mundipharma, Roche, BMJ Journals, MedMedia, Astra Zeneca, AbbVie, Lilly, Medahead, Daiichi Sankyo, Sanofi, Merck Sharp & Dome, Tocagen, Adastra Contracted Research: Boehringer-Ingelheim, Bristol-Myers Squibb, Roche, Daiichi Sankyo, Merck Sharp & Dome, Novocure, GlaxoSmithKline, AbbVie (all payments received by faculty’s institution) Honoraria: Bayer, Bristol-Myers Squibb, Novartis, Gerson Lehrman Group (GLG), CMC Contrast, GlaxoSmithKline, Mundipharma, Roche, BMJ Journals, MedMedia, Astra Zeneca, AbbVie, Lilly, Medahead, Daiichi Sankyo, Sanofi, Merck Sharp & Dome, Tocagen, Adastra |
| Trenton A. Pritt | Author | Nothing to disclose |
| Kerry L. Reynolds | Author | Nothing to disclose |
| Chantal Saberian | Author | Nothing to disclose |
| Sarah Sammons | Author | Consulting Fees (e.g., Advisory Board): Novartis, AstraZeneca, Daiichi Sankyo, Foundation Medicine, Sermonix Contracted Research: Eli Lilly, AbbVie, Sermonix, Bristol Meyers Squibb, Novartis |
| Ugur Sener | Author | Nothing to disclose |
| Helen A. Shih | Author | Nothing to disclose |
| David B. Schultz | Author | Nothing to disclose |
| Scott G. Soltys | Author | Contracted Research: Novocure, Inc. Speaker’s Bureau: Zap Surgical, Inc. |
| Paul Sperduto | Author | Nothing to disclose |
| Samuel A. Sprowls | Author | Nothing to disclose |
| Ethan S. Srinivasan | Author | Nothing to disclose |
| Adriane Steindl | Author | Nothing to disclose |
| Hussein A. Tawbi | Author | Consulting Fee (e.g., Advisory Board): BMS, Merck, Genentech, Novartis, Eisai, Iovance, Karyopharm, Boxer Capital Contracted Research: BMS, Merck, Genentech, Novartis, GSK, EMD Serono |
| Manuel Valiente | Author | Nothing to disclose |
| Amanda E. D. Van Swearingen | Author | Nothing to disclose |
| Heather A. Wakelee | Author | Consulting Fee (e.g., Advisory Board): AstraZeneca, Xcovery, Janssen, Daiichi Sankyo, Mirati, Blueprint, Helsinn Contracted Research: ACEA Biosciences, Arrys Therapeutics, AstraZeneca/Medimmune, BMS, Celgene, Clovis Oncology, Exelixis, Genentech/Roche, Gilead, Merck, Novartis, Pharmacyclics, Seattle Genetics, Xcovery, Eli Lilly, Pfizer Honoraria: Novartis, AstraZeneca |
| Jianbo Wang | Author | Nothing to disclose |
| Jeffrey S. Wefel | Author | Consulting Fee (e.g., Advisory Board): Angiochem, Bayer, GT Medical Technology, Juno, Novocure, Roche, Vanquish Oncology |
| Frank Winkler | Author | Consulting Fee (e.g., Advisory Board): D&C Europa Ltd. Contracted Research: Boehringer, GSK, Roche, Genentech, Divide & Conquer |
| Helena Yu | Author | Consulting Fee (e.g., Advisory Board): Daiichi, AstraZeneca, Blueprint Medicine, Janssen Contracted Research: Funding to my institution from Daiichi, AstraZeneca, Cullinan, Pfizer, Novartis |
| Gelareh Zadeh | Author | Nothing to disclose |
| Jeffrey A. Zuccato | Author | Nothing to disclose |
| The editors reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity: | ||
| Name of Editor | Role | Reported Financial Relationship |
| Carey K. Anders | Editor | Consulting Fee (e.g., Advisory Board): Genentech, Eisai, IPSEN, Seattle Genetics, Astra Zeneca, Novartis, Immunomedics, Elucida, Athenex Contracted Research: PUMA, Lilly, Merck, Seattle Genetics, Nektar, Tesaro, G1-Therapeutics, ZION, Novartis, Pfizer |
| Priscilla K. Brastianos | Editor | Consulting Fee (e.g., Advisory Board): Pfizer, ElevateBio, Dantari, SK Life Sciences, Sintetica, Voyager Therapeutics Contracted Research: Merck, Eli Lilly, BMS, Mirati Honoraria: Pfizer |
| David B. Schultz | Editor | Nothing to disclose |
| Jeffrey A. Zuccato | Editor | Nothing to disclose |
| The Reviewers reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity: | ||
| Name of Reviewer | Role | Reported Financial Relationship |
| Mohammed Ali Alvi | Reviewer | Nothing to disclose |
| Hidefumi Aoyama | Reviewer | Nothing to disclose |
| Stephen Bagley | Reviewer | Consulting Fee (e.g., Advisory Board): Novocure, Sumitomo Dainippon Contracted Research: Incyte, Eli Lilly, GlaxoSmithKline, Novocure |
| Priscilla K. Brastianos | Reviewer | Consulting Fee (e.g., Advisory Board): Pfizer, ElevateBio, Dantari, SK Life Sciences, Sintetica, Voyager Therapeutics Contracted Research: Merck, Eli Lilly, BMS, Mirati Honoraria: Pfizer |
| Samuel Chao | Reviewer | Contracted Research: Blue Earth Diagnostics Honoraria: Varian Medical System |
| Erin M. Dunbar | Reviewer | Nothing to disclose |
| Gaetano Finocchiaro | Reviewer | Nothing to disclose |
| Isabella Glitza Olivia | Reviewer | Consulting Fee (e.g., Advisory Board): BMS, Array, Novartis Contracted Research: BMS, Merck, Pfizer |
| Jerome Graber | Reviewer | Nothing to disclose |
| Jason Huse | Reviewer | Nothing to disclose |
| Randy Jensen | Reviewer | Consulting Fee (e.g., Advisory Board): Medtronic |
| Raja B. Khan | Reviewer | Nothing to disclose |
| Albert E. Kim | Reviewer | Nothing to disclose |
| Manabu Kinoshita | Reviewer | Nothing to disclose |
| Rupesh Kotecha | Reviewer | Consulting Fee (e.g., Advisory Board): Viewray Inc., Novocure Inc. Contracted Research: Medtronic Inc, Blue Earth Diagnostics, Novocure Inc., GT Medical Technologies, AstraZeneca, Exelixis, Viewray Inc Honoraria: Accuray Inc., Elekta AB, Novocure Inc., Viewray Inc. Speakers’ Bureau: Novocure Inc |
| Andrew B. Lassman | Reviewer | Consulting Fee (e.g., Advisory Board): Abbott, AbbVie, Forma, Bioclinica (as an expert, blinded, independent reviewer of deidentified clinical data for a BMS-sponsored trial), GSK, Karyopharm, Bayer, PER/MLH Holdings, Novocure, Orbus, QED, Sapience Contracted Research: Genentech/Roche, Millenium, Celldex, Pfizer, Aeterna Zenaris, Novartis, QED, Karyopharm, AbbVie, Kadmon, BI Vaccines, Beigene, Oncoceutics, Bayer, Agios, Orbus, |
| Justin D. Lathia | Reviewer | Nothing to disclose |
| Eudocia Lee | Reviewer | Nothing to disclose |
| Nancy U. Lin | Reviewer | Consulting Fee (e.g., Advisory Board): Puma, Seattle Genetics, Daiichi Sankyo, AstraZeneca, Denali Therapeutics, Prelude Therapeutics, Pfizer Contracted Research: (all funding to institution) -- Genentech, Merck, Seattle Genetics, Pfizer, Novartis, AstraZeneca |
| Mihaela Lorger | Reviewer | Nothing to disclose |
| Ashlee Loughan | Reviewer | Nothing to disclose |
| Edjah Nduom | Reviewer | Contracted Research: Bristol-Myers Squibb. Receiving Drug-only support for clinical trial |
| David Peereboom | Reviewer | Consulting Fee (e.g., Advisory Board): Orbus Therapeutics, Inc., Sumitomo Dainippon Pharma Oncology, Inc. Contracted Research: Stemline Therapeutics, Pfizer, Novartis, NeOnc Technologies, Bristol-Myers Squibb, Genentech/Roche, Mylan Pharmaceuticals, Orbus Therapeutics, Pharmacyclics LLC, Incyte, Bayer, Mimivax |
| Maryam Rahman | Reviewer | Nothing to disclose |
| Analiz Rodriguez | Reviewer | Nothing to disclose |
| Takashi Sasayama | Reviewer | Nothing to disclose |
| David Schiff | Reviewer | Consulting Fee (e.g., Advisory Board): Glaxo Smith Kline (advisory board), Orbus and Denovo (DSMC) |
| Patricia Steeg | Reviewer | Nothing to disclose |
| Roy Strowd | Reviewer | Consulting Fee (e.g., Advisory Board): Monteris Medical, Novocure Contracted Research: Jazz Pharmaceuticals |
| Jennie Taylor | Reviewer | Contracted Research: Agios, BMS, Navio, AbbVie |
| Mehdi Touat | Reviewer | Consulting Fee (e.g., Advisory Board): Agios Pharmaceuticals Contracted Research: Sanofi |
| Seiichi Yoshida | Reviewer | Nothing to disclose |
| Gelareh Zadeh | Reviewer | Nothing to disclose |
| The planners and managers reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity: | ||
| Name of Planner or Manager | Role | Reported Financial Relationship |
| Lindsay Borvansky | Clinical Content Reviewer | Nothing to disclose |
| Andrea Funk | Planner/Manager | Nothing to disclose |
| Liddy Knight | Planner/Manager | Nothing to disclose |
| Ashley Cann | Planner/Manager | Nothing to disclose |
| Kim Rodriguez | Planner/Manager | Nothing to disclose |
| Angie Ames | Planner/Manager | Nothing to disclose |
| MeLesa Ritterhouse | Planner/Manager | Nothing to disclose |
| Charles Haynes | Planner/Manager | Nothing to disclose |
| Gelareh Zadeh | Planner/Manager | Nothing to disclose |
| Carey K. Anders | Planner/Manager | Consulting Fee (e.g., Advisory Board): Genentech, Eisai, IPSEN, Seattle Genetics, Astra Zeneca, Novartis, Immunomedics, Elucida, Athenex Contracted Research: PUMA, Lilly, Merck, Seattle Genetics, Nektar, Tesaro, G1-Therapeutics, ZION, Novartis, Pfizer |
| Phil Bishop | Planner/Manager | Nothing to disclose |
| Priscilla K. Brastianos | Planner/Manager | Consulting Fee (e.g., Advisory Board): Pfizer, ElevateBio, Dantari, SK Life Sciences, Sintetica, Voyager Therapeutics Contracted Research: Merck, Eli Lilly, BMS, Mirati Honoraria: Pfizer |
| Elizabeth Anne Martinson | Planner/Manager | Nothing to disclose |
| David B. Schultz | Planner/Manager | Nothing to disclose |
| Jeffrey A. Zuccato | Planner/Manager | Nothing to disclose |