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(A) Schematic illustration of preparation of CCNV/DOX/HPPH as in Situ DC Vaccine for synergistically inducing ICD by chemotherapy and PDT, CTL activation and vaccine immunotherapy. (B) Flow cytometry characterization of CRT exposure by measuring various formulations stained with specific fluorescent probe of CRT. (C) Frequency of CD3+CD8+ TILs in tumors treated with different formulations. Reproduced with permission 144. Copyright 2019, American Chemical Society.
