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. 2021 Dec 8;9(12):1859. doi: 10.3390/biomedicines9121859

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The relationship between PLT activation and mitochondrial respiration of PLT in the S-pathway. Respiration of permeabilized PLT in the S-pathway (S_E, expressed as FCR normalized for ET capacity E of living cells, FCR = S_E/E), and PLT activation expressed as a percentage of CD62P positive cells. (A) Regression analysis according to [49] where the red dotted line represents ordinary Y/X regression and the black dotted line represents ordinate projection of abscissal regression with inverted parameters X/Y, and the grey line represents mean regression line; r² is independent of axes inversion. (B) Data points for individual blood donors are connected by a full line from DC (triangles) to PA (circles) and WA (squares); each color indicates a different donor.