Table 5.

Predicted amino acid substitution in the PA protein.

pagA Mutation	Predicted Amino Acid Substitution in the Unprocessed PA	Domain of PA	Number of Strains
17T→C	6V→A	Signal peptide	1
59G→A	20S→N	Signal peptide	1
95A→C	32K→T	I	1
195C→T	- *		64
196T→C	66S→P	I, 1β2	4
869T→G	290I→S	II	3
981A→T	-		17
1297A→G	433I→V	II	3
1693C→T	565P→S	III	6
1765C→A	589Q→K	III	1
1799C→T	600A→V	III	61
1803T→C	-		1

* synonymous mutation.