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. 2021 Nov 30;13(12):2049. doi: 10.3390/pharmaceutics13122049

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Plasma concentrations (a) and brain concentrations (b) of tarenflurbil (TFB). Values are expressed as mean ± SD (n = 4). ** p < 0.0001 when compared with TFB administered by IV solution, IN solution and oral suspension, ^†† p < 0.0001 when compared with TFB-NPs and ^† p < 0.01 when compared with TFB-NPs. Adapted with permission from [139], Elsevier, 2016.