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. 2021 Nov 25;13(12):2002. doi: 10.3390/pharmaceutics13122002

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Composition of the single capsules of size 00 (left) and composition of the size 3 capsule in size 00 capsule formulations (mid), (B) T1 weighted VIBE of in vitro disintegration of hard capsule with hibiscus tea powder in water, (C) T2*/T1 weighted TRUFI of in vivo disintegration of hard capsule surrounded by water in stomach.