Table 3.

Sensitivity analysis of the ability to discriminate between recent exacerbation and no-exacerbation in different subpopulation.

	Training AUC	Cross-Validated AUC	Validation AUC
All asthma patients (n = 361)	0.78 (0.72–0.84)	0.76 (0.70–0.83)	0.76 (0.64–0.87)
Without antibiotics users (n = 333) *	0.81 (0.75–0.87)	0.79 (0.72–0.85)	0.81 (0.70–0.92)
Without current smokers (n = 338)	0.77 (0.71–0.84)	0.75 (0.68–0.82)	0.74 (0.60–0.87)
Only with patients who use maintenance ICS (n = 308)	0.83 (0.78–0.89)	0.81 (0.76–0.87)	0.84 (0.75–0.93)

* Defined as use of antibiotics for acute worsening of respiratory symptoms < 3 months prior measurement. AUC: area under the curve and ICS: inhaled corticosteroids. Data is shown as AUC with 95% confidence interval.